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Can’t Stop the Nitro Groups

10:06 EDT 15 Aug 2019 | Science

OK, since I’m a medicinal chemist, I have an excellent excuse to avoid the nitro functional group. It’s metabolic trouble, and although there are indeed drugs with nitros on them, they’re exceptions. Some of them, in fact, are antibacterials that rely on that metabolic activation to work, in the same way that there are nitrate

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