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Researchers have found that levels of methylated microRNA were significantly higher in tissue and serum from cancer patients compared with that from normal controls. Specifically, methylation levels in serum samples distinguished patients with early pancreatic cancer from healthy controls with extremely high sensitivity and specificity. These findings provide a basis for new diagnostic strategies for early-stage cancer and represent a new perspective for understanding microRNA biology.
Original Article: Methylation of microRNA may be a new powerful biomarker for cancerNEXT ARTICLE
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals, and some viruses. Key findings: miRNA is involved in the normal functioning of eukaryotic cells, so has dysregulation...
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The pancreas secretes a number of important hormones into the digestive tract and the blood stream. Cancers are most commonly exocrine than endocrine (neuroendocrine) tumors. Functional tumors secrete hormones; Insulinoma, Gastrinoma, Somatostatinoma, VI...