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Researchers have found that the ancient RND-type multidrug efflux pump AcrB from Haemophilus influenzae targets the same drugs as its more evolved counterpart from Escherichia coli, showing that multidrug resistance is an ancient trait. The more ancient protein is unaffected by efflux pump inhibitors, which were designed to target the evolved pumps. Understanding these evolutionary differences will help researchers develop targeted therapies against multidrug-resistant bacterial pathogens.
Original Article: Multidrug resistance: Not as recent as we thoughtNEXT ARTICLE
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...