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[Comment] The dawn of robust individualised risk models for dementia

21:33 EDT 13 Sep 2019 | The Lancet

Mild cognitive impairment (MCI) typically represents a holding pattern for individuals who live for many years without knowing their long-term prognosis. Such uncertainty between improvement or remaining stable versus progressing to a diagnosis of dementia is unsatisfying. Scarcity of specific information or advice compounds this issue. People with MCI do not have access to treatments such as cholinesterase inhibitors or memantine, they usually cannot partake in therapeutic trials, and the absence of a path forward can add to their anxiety and that of family members.

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