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AstraZeneca's Imfinzi triple combo beats chemo in treatment-naive metastatic lung cancer

06:05 EDT 29 Oct 2019 | Pharmafile

AstraZeneca has unveiled positive new Phase 3 data for the combination of Imfinzi (durvalumab) and anti-CTLA4 antibody tremelimumab with chemotherapy in treatment-naïve metastatic non-small cell lung cancer (NSCLC), showing that the therapy met its primary endpoint in the trial.

In a study comparing the efficacy of Imfinzi plus one of five standard-of-care platinum-based chemotherapy options versus chemo alone, the aforementioned combo was shown to generate a “statistically significant and clinically meaningful improvement” in progression-free survival.

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Original Article: AstraZeneca's Imfinzi triple combo beats chemo in treatment-naive metastatic lung cancer

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