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Roche terminates Duchenne muscular dystrophy candidate due to poor clinical outlook

07:12 EST 8 Nov 2019 | Pharmafile

Roche has revealed its decision to terminate further development of its anti-myostatin adnectin protein agent RG6206 after it became apparent that the candidate would not come to show clinical benefit in the treatment of Duchenne muscular dystrophy (DMD).

The firm shut down its Phase 2/3 trial investigating the drug following a futility analysis. The study was evaluating the drug in 166 ambulatory male patients between the ages of six and 11, measuring benefit according to the North Star Ambulatory Assessment (NSAA) total score.  

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Original Article: Roche terminates Duchenne muscular dystrophy candidate due to poor clinical outlook

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