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Suzhou's CStone Pharma released positive results from a China Phase II trial of its PD-L1 candidate (CS1001) as a monotherapy in relapsed or refractory extranodal natural killer/T-cell lymphoma (rr-ENKTL). CS1001 produced an overall response rate of 41%, a complete and durable response rate of 32% and a benign safety profile. The company says studies have shown links between Epstein-Barr virus (EBV) infection and ENKTL. EBV infection induces immune tolerance by upgrading PD-L1 expression in tumor cells, promoting tumor growth. CStone is developing a pipeline of 15 oncology drug candidates. More details....
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Original Article: CStone's PD-L1 Candidate Shows Positive Results for LymphomaNEXT ARTICLE
In a clinical trial or interventional study, participants receive specific interventions according to the research plan or protocol created by the investigators. These interventions may be medical products, such as drugs or devices; procedures; or change...
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