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Vitamin D and Health Outcomes

19:00 EST 7 Nov 2019 | JAMA

Not long ago, vitamin D was riding high. Beyond its role in calcium homeostasis and bone health, animal studies linked vitamin D deficiency to numerous chronic illnesses including hypertension, diabetes, autoimmunity, and malignancy. Corroborating human observational studies reported associations between vitamin D deficiency and increased risks of hypertension, diabetes, cardiovascular disease, autoimmunity, and cancer. The lay press seized on this chorus of observational studies, testing of serum 25-hydroxyvitamin D levels proliferated, and supplementation with cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) increased substantially.

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