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Rapid generation and selection of Cas9-engineering TRP53 R172P mice that do not have off-target effects

19:00 EST 7 Nov 2019 | BioMed Central

Genetic mutations cause severe human diseases, and suitable animal models to study the regulatory mechanisms involved are required. The CRISPR/Cas9 system is a powerful, highly efficient and easily manipulated...

Original Article: Rapid generation and selection of Cas9-engineering TRP53 R172P mice that do not have off-target effects

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