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[Articles] Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

21:09 EST 3 Dec 2019 | The Lancet

Our study showed that age at symptom onset and at death of people with genetic frontotemporal dementia is influenced by genetic group and, particularly for MAPT mutations, by the specific mutation carried and by family membership. Although estimation of age at onset will be an important factor in future pre-symptomatic therapeutic trials for all three genetic groups, our study suggests that data from other members of the family will be particularly helpful only for individuals with MAPT mutations.

Original Article: [Articles] Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

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