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(Chinese Academy of Sciences Headquarters) The research team led by Prof. LU Xuefeng from the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences (CAS), revealed the catalytic mechanism and structure-function relationship of the specific and efficient lovastatin hydrolase PcEST.
Original Article: Scientists reveal catalytic mechanism of lovastatin hydrolaseNEXT ARTICLE
Statins (or HMG-CoA reductase inhibitors) are a class of drug used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Increased cholesterol levels have been as...