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Destroying DNA to save the genome -- study offers new insights into sepsis and its treatment

20:00 EDT 25 Mar 2020 | AAAS

(Cactus Communications) Sepsis is a life-threatening condition that kills millions annually; it is poorly understood and has no specific treatment. Now, researchers from Tata Memorial Centre, India, led by Prof. Dr Indraneel Mittra, have uncovered an important molecular mechanism underlying different aspects of sepsis--chromatin released by dying host cells after infection or injury. The scientists also put forth a novel treatment strategy for sepsis, which targets cell-free chromatin.

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