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Nutrition Research

15:03 EDT 19th September 2018 | BioPortfolio

Ultra-stretchable Multilayered Fiber with a Hollow-Monolith Structure for High Performance Strain Sensor.

As a crucial component of data terminal acquisition devices, flexible strain sensor has shown promising applications in numerous fields, such as healthcare, bodynet, intelligent traffic system and robotic system. For stretchable strain sensor, it remains a giant challenge to realize a fine balance of wide detection range and high sensitivity. Here, an electrically conductive carbon nanotubes (CNTs...

Linking of psoriasis with osteopenia and osteoporosis: A cross-sectional study.

Psoriasis is a multisystem disease which has been related to vitamin-D deficiency through chronic inflammation. This psoriasis-related inflammatory state and vitamin-D deficiency may induce bone mineral density loss. The purpose of this study is to assess the relationship of psoriasis with bone mineral density, by comparing psoriatic patients with healthy controls and patients with osteopenia/oste...

Ultraviolet light-induced gasdermin C expression is mediated via TRPV1/calcium/calcineurin/NFATc1 signaling.

Gasdermin (GSDM)‑C is a member of the GSDM gene family and is expressed in the epithelial cells of various tissue types, including skin. GSDMC expression is induced by ultraviolet (UV) irradiation and contributes to UV‑induced matrix metalloproteinase 1 expression in human skin keratinocytes. However, how UV irradiation induces GSDMC expression remains unclear. The present study aimed to inves...

Tamoxifen inhibits the proliferation of non‑melanoma skin cancer cells by increasing intracellular calcium concentration.

Tamoxifen is an estrogen receptor (ER) antagonist used as first-line chemotherapy in breast cancer. Recent studies suggest that tamoxifen may be effective not only for ER‑positive but also for ER‑negative cancer cases. The aim of the present study was to investigate the antiproliferative effect of tamoxifen against human non‑melanoma skin cancer cells. Tamoxifen inhibited the proliferation o...

DROPLET MOBILITY ON HYDROPHOBIC FIBROUS COATINGS COMPRISED OF ORTHOGONAL FIBERS.

Water droplet mobility on a hydrophobic surface cannot be guaranteed even when the droplet exhibits a high contact angle (CA) with the surface. In fact, droplet mobility on a surface, especially a fibrous surface, has remained an unsolved empirical problem. This paper is a combined experimental-computational study focused on droplet mobility on a fibrous surface. Electrospun Polystyrene (PS) coati...

Maternal feeding practices in relation to dietary intakes and BMI in 5 year-olds in a multi-ethnic Asian population.

In Asia, little is known about how maternal feeding practices are associated with dietary intakes and body mass index (BMI) in preschoolers.

Too picky for my taste? The effect of the gluten-free dietary restriction on impressions of romantic partners.

Millions of individuals world-wide adhere to a gluten-free diet and this dietary trend is on the rise. The present research identified a consumption stereotype of those following a gluten-free diet and tested whether this stereotype influenced impressions and interest in a potential romantic partner. We also assessed whether being gluten-free differentially impacted impressions of males compared t...

Cancer-specific chemotherapeutic strategy based on the vitamin K3 mediated ROS regenerative feedback and visualized drug release in vivo.

A promising theranostic nanosystem VK3-CPT@Ru-CD is designed and fabricated by the host-guest driven self-assembly between the fluorescent adamantine-functionalized Ru(II) complexes and the ROS-labile-cyclodextrin modified thioketal linkers, in which anticancer drug camptothecin (CPT) and vitamin K3 (VK3) are effectively co-encapsulated. On account of the generative feedback between the intracellu...

Effects of live yeast dietary supplementation on hormonal profile, ovarian follicular dynamics, and reproductive performance in dairy cows exposed to high ambient temperature.

Two experiments were conducted to investigate the effects of dietary supplementation with live yeast culture on hormonal profile, ovarian follicular dynamics and reproductive performance of lactating dairy cows exposed to high ambient temperature. In Expt. 1, Holstein cows were fed a diet with (n = 6) or without (n = 6) 4 g yeast/h/d from 21 d before expected calving date until 8 weeks...

Injectable Hydrogel of Vitamin B9 for Controlled Release of Both Hydrophilic and Hydrophobic Anticancer Drugs.

Folic acid (FA), vitamin-B9, is a good receptor of drugs triggering cellular uptake via endocytosis. FA is sparingly soluble in water and here a new approach for formation of FA hydrogel at physiological condition is reported using hydrolysis of glucono-δ-lactone in PBS buffer. The gel has fibrillar network morphology arising from intermolecular H-bonding and π-stacking interaction. Thixotropic ...

A Highly Conductive Fiber with Waterproof and Self-cleaning Properties for Textile Electronics.

Major concerns in developments of wearable textile electronics are exposure to moisture and contamination. The exposure can cause electrical breakdown of the device and its interconnections, thus continuous efforts have been made to fabricate textile electronics which are free from moisture and pollution. Herein, we developed a highly conductive and waterproof fiber with excellent electrical condu...

Effects of Protein Corona on Active and Passive Targeting of Cyclic RGD Peptides Functionalized PEGylation Nanoparticles.

Protein corona can alter the physiochemical properties of targeting nanoparticles (NPs), as well as their physiological responses and targeting functionality. Herein, we synthesized 20 types of NPs with diverse surface chemistry in order to study the impacts of protein corona on targeting functionality of cyclic RGD peptides, and their relationships to the polyethylene glycol (PEG) length and graf...

Prospective Safety Evaluation of a Cardiovascular Health Dietary Supplement in Adults with Prehypertension and Stage I Hypertension.

To prospectively examine the long-term safety of a cardiovascular health dietary supplement by assessing a comprehensive set of safety measures.

Drug-induced bone loss: a major safety concern in Europe.

Drug-induced bone loss remains the major cause of vertebral and hip fractures and significantly associated to morbidity and mortality. This article will review the common drugs identified as the causes of bone loss and the risk factors and management in European countries. Areas covered: Apart from glucorticoid - the most reputed cause of osteoporosis, many different drugs could cause harmful skel...

The role of calcium sensing receptors in GLP-1 and PYY secretion after acute intraduodenal administration of L-Tryptophan in rats.

The calcium-sensing receptor (CaSR), the major sensor of extracellular Ca, is expressed in various tissues, including the gastrointestinal tract. Although the essential ligand of CaSR is calcium, its activity can be regulated by aromatic L-amino acids. The expression of CaSR on enteroendocrine cells suggests that CaSR functions as a physiological amino acid sensor for gut hormone release. Here, we...

Vitamin D to Prevent Lung Injury Following Esophagectomy-A Randomized, Placebo-Controlled Trial.

Observational studies suggest an association between vitamin D deficiency and adverse outcomes of critical illness and identify it as a potential risk factor for the development of lung injury. To determine whether preoperative administration of oral high-dose cholecalciferol ameliorates early acute lung injury postoperatively in adults undergoing elective esophagectomy.

Identification of insulin-regulated aminopeptidase (IRAP) in the rat pineal gland and the modulation of melatonin synthesis by angiotensin IV.

A local renin-angiotensin system (RAS) has been postulated in the pineal gland. In addition to angiotensin II (Ang II), other active metabolites have been described. In this study, we aimed to investigate a role for Ang IV in melatonin synthesis and the presence of its proposed (IRAP)/AT receptor (insulin-regulated aminopeptidase) in the pineal gland. The effect of Ang IV on melatonin synthesis wa...

Mucosal immune parameters, immune and antioxidant defence related genes expression and growth performance of zebrafish (Danio rerio) fed on Gracilaria gracilis powder.

In the present study zebrafish (Danio rerio) has been used as model organism to establish the effects of dietary supplementation of Gracilaria gracilis powder (GP) on mucosal and innate immune parameters, antioxidant enzymes, and growth. In order to establish these features, zebrafish were fed for eight weeks with experimental diets containing different levels of Red algae, 0.25, 0.5 and 1% of GP;...

Dietary Intake Among Head Start Preschooler-caregiver Dyads.

The purpose of this study was to examine the relationship between Head Start preschooler-caregiver dyad's dietary intake and factors influencing dietary intake.

Effect of partial dietary replacement of fishmeal by yellow mealworm (Tenebrio molitor) larvae meal on the innate immune response and intestinal antioxidant enzymes of rainbow trout (Oncorhynchus mykiss).

The present study investigated the effects of 25 and 50% dietary inclusion of yellow mealworm, Tenebrio molitor (TM), larvae on the intestinal antioxidant enzymes, lipid peroxidation and immune system of rainbow trout, Oncorhynchus mykiss. Fish were fed for 90 days with a control diet (TM0) or with 2 test diets (TM25 and TM50) where 35 and 67% of the fishmeal was replaced by TM larvae meal respect...

Effect of varying prepartum dietary cation-anion difference and calcium concentration on postpartum mineral and metabolite status and milk production of multiparous cows.

Eighty-two multiparous Holstein cows were enrolled 28 d before expected calving and assigned to 1 of 4 dietary treatments in a randomized block design experiment with a 2 × 2 factorial arrangement of treatments to determine the effect of feeding a neutral or acidogenic diet varying in Ca concentration on prepartum and postpartum intake, blood mineral and metabolite concentrations, and postpartum ...

Effects of sunlight exposure and vitamin D supplementation on vitamin D levels in postmenopausal women in rural Thailand: A randomized controlled trial.

Despite the abundant sunlight in Thailand, vitamin D deficiency is common in premenopausal and postmenopausal Thai women. Sunlight exposure is a natural way to increase one's intake of vitamin D. However, limited research has been conducted regarding natural exposure to sunlight as a strategy to improve vitamin D status in postmenopausal women.

Regulation of Endoplasmic Reticulum-Mitochondria contacts by Parkin via Mfn2.

Parkin, an E3 ubiquitin ligase and a Parkinson's disease (PD) related gene, translocates to impaired mitochondria and drives their elimination via autophagy, a process known as mitophagy. Mitochondrial pro-fusion protein Mitofusins (Mfn1 and Mfn2) were found to be a target for Parkin mediated ubiquitination. Mfns are transmembrane GTPase embedded in the outer membrane of mitochondria, which are re...

Relationship between dietary quality, determined by DASH score, and cardiometabolic health biomarkers: A cross-sectional analysis in adults.

The relationship between dietary patterns and cardiometabolic disease is of increasing interest. However, limited data regarding the association between dietary quality and biomarkers of cardiometabolic health exist. Therefore the aim of this work was to examine potential associations between dietary quality, assessed using the Dietary Approaches to Stop Hypertension (DASH) dietary quality score, ...

Vitamin D status after colorectal cancer diagnosis and patient survival according to immune response to tumour.

High-level plasma 25-hydroxyvitamin D [25(OH)D] has been associated with lower colorectal cancer incidence and mortality. Considering evidence indicating immunomodulatory effects of vitamin D, we hypothesised that survival benefits from high systemic vitamin D level might be stronger for colorectal carcinoma with lower immune response to tumour.

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