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Obstetrics and gynaecology (OB/GYN, OBG, O&G or Obs & Gynae) Research

02:25 EDT 24th May 2018 | BioPortfolio

Reproductive, physiological, and molecular outcomes in female mice deficient in Dhh and Ihh.

Ovarian development requires coordinate communications between oocytes, granulosa cells, and theca cells. Two Hedgehog (Hh) pathway ligands, desert (Dhh) and indian hedgehog (Ihh), are produced by the granulosa cells and work together to regulate theca cell specification and development. Mice lacking both Dhh and Ihh resulted in the loss of normal ovarian function and raised the question of which ...

Accuracy of visual inspection performed by community health workers in cervical cancer screening.

Cervical cancer remains the leading cause of cancer and mortality in low-resource areas with healthcare personnel shortages. Visual inspection is a low-resource alternative method of cervical cancer screening in areas with limited access to healthcare.

Evaluation of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome.

To investigate the efficacy of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome (PMS).

Alternative splicing of GnRH2 and GnRH2-associated peptide plays roles in gonadal differentiation of the rice field eel, Monopterus albus.

The rice field eel, Monopterus albus, is a protogynous hermaphrodite fish, in which the gonads are initially female ovaries which then transform into male testes. The exact mechanisms governing sex reversal in the rice field eel are unknown. In this study, a novel alternative splicing variant of GnRH2 (GnRH2-SV), retaining the second intron, was discovered in the gonad of the rice field eel. Compa...

Non-malignant Sequelae Following Unconfined Power Morcellation.

To identify the incidence of repeat surgery and subsequent findings following the performance of unconfined uterine power morcellation.

Extracts of compound Muniziqi granule suppressed uterus contraction and ameliorated oxytocin-inducedprimary dysmenorrhea.

Compound Muniziqi granule (CMG) is usually used as a traditional Uighur medicine to treat acne, chloasma, skin inflammation, primary dysmenorrhea (PDM), and menopausal syndrome. However, there are no sufficient data to support the clinic uses of CMG in PDM.

Vesicovaginal fistula repair through combined transurethral and transvaginal approaches: a case series study.

We report a case series study on five patients who underwent combined transurethral and transvaginal approaches to repair their vesicovaginal fistulas. All of them had failed the previous surgical treatments for their fistulas. Combined transurethral and transvaginal approaches successfully repaired their vesicovaginal fistulas, with minimal intraoperative bleeding and rapid postoperative recoveri...

Estrogen Receptor, Progesterone Receptor & CD8+ Expression in Endometrium of Women of Unexplained Infertility.

The present study aimed to investigate the changes of endometrial progesterone and estrogen receptors in luteal phase biopsy specimens of infertile women and find a correlation, if any, between these and CD8+ receptors in the same.

Retrospective study on the management and follow-up of 18 patients with a mid-urethral sling penetrating the urethra or bladder.

The mid-urethral sling (MUS) procedure is the gold-standard for the surgical treatment of stress urinary incontinence (SUI). Urethro-vesical sling exposure is one of the most serious complications of this procedure. We describe the treatment and follow-up of 18 patients with bladder or urethral sling exposure.

Premature progesterone rise on day of hCG negatively correlated with live birth rate in IVF cycles: an analysis of 1,022 cycles.

To investigate the relationship between serum P levels on the day of hCG administration and pregnancy outcomes in patients undergoing IVF.

Severe pain in women undergoing first-trimester surgical abortion under local anaesthesia: A closer look at the predictive factors.

Androgen Excess- Polycystic Ovary Syndrome Society: position statement on depression, anxiety, quality of life, and eating disorders in polycystic ovary syndrome.

To formulate clinical consensus recommendations for screening depression, anxiety, health-related quality of life (HRQoL), and disordered eating symptoms in women with polycystic ovary syndrome (PCOS) and review prevalence based on phenotypes and ethnicity, changes over time, etiology, and impact of treatment.

Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice.

Reactive oxygen species (ROS) produced in biological reactions have been shown to contribute to ovarian aging. Peroxiredoxin 2 (Prx2) is an antioxidant enzyme that protects cells by scavenging ROS; however, its effect on age-related, oxidative stress-associated ovarian failure has not been reported. Here, we investigated its role in age-related ovarian dysfunction and 4-vinylcyclohexene diepoxide ...

Cumulative live birth rates after IVF in patients with polycystic ovaries: phenotype matters.

Do cumulative live birth rates (CLBR) vary among women with different polycystic ovary syndrome (PCOS) phenotypes who undergo IVF/intracytoplasmic sperm injection (ICSI) treatment?

Vasopressin during laparoscopic myomectomy: Does it really extend its limits?.

Τo investigate whether the use of vasopressin played an important role in the safe expansion of the indications of laparoscopic myomectomy in our practice.

Association between unexplained thickened nuchal translucency and adverse pregnancy outcomes.

To determine the association between unexplained increased nuchal translucency (INT) and adverse pregnancy outcomes.

Management of postpartum hemorrhage with free-flow pressure controlled uterine balloon.

The free-flow pressure controlled uterine balloon (Ellavi UBT; Sinapi biomedical, Stellenbosch, South Africa) allows the expulsion of water from the balloon to reduce volume and pressure control by adjusting the height of the supply bag above the patient. The balloon can be filled to a capacity of 750 mL without requiring expansion pressure. The device is affordable for use in lesser resourced cou...

Modified extraperitoneal uterosacral ligament suspension for prevention of vault prolapse after vaginal hysterectomy.

During vaginal hysterectomy, extraperitoneal uterosacral ligament suspension (ULS) bites can be taken before removing the uterus. We evaluated this modified extraperitoneal ULS for vault prolapse prevention.

Placenta accreta and balloon catheterization: the experience of a single center and an update of latest evidence of literature.

We studied the efficacy of using pre-cesarean delivery (CD) temporary occlusion of internal iliac arteries with balloon catheters in case of placenta previa-accreta in terms of maternal and neonatal outcomes and to test accuracy of ultrasound (US) and magnetic resonance imaging (MRI) for prenatal diagnosis.

Cytological assessment of endometrial washings obtained with Karman cannula using a liquid-based preparation method for the detection of endometrial pathologies.

The aim of this study was to evaluate the diagnostic efficacy and utility of liquid-based cytology in ThinPrep (Cytyc Corporation, Boxborough, MA) for endometrial lesions in patients presenting with abnormal uterine bleeding.

Intrauterine HPV transmission: a systematic review of the literature.

To evaluate the percentage of intrauterine vertical human papillomavirus (HPV) transmission among HPV-positive mothers and the relative risk of intrauterine vertical HPV transmission between cesarean and vaginal delivery among HPV-positive women.

The effect of labor epidural analgesia on maternal-fetal outcomes: a retrospective cohort study.

To evaluate the impact of labor epidural analgesia on maternal-fetal safety outcomes in a signal Chinese academic medical center.

Three dimensional model of the female perineum and pelvic floor muscles.

The anatomy of the perineum and the pelvic diaphragm of woman is complex. A numerical complete three-dimensional (3D) model of every muscle of the woman pelvis doesn't exist. The pathophysiology of genital prolapse is still debated. Knowledge of anatomy is essential to better understand its mechanisms. The aim of this research was to build a complete three-dimensional model of the female perineum ...

Cross-cultural adaptation and validation of the Functional Assessment of Chronic Illness Therapy - Cervical Dysplasia (FACIT-CD) questionnaire for Serbian women.

The FACIT-CD (Functional Assessment of Chronic Illness Therapy - Cervical Dysplasia) questionnaire is a disease-specific instrument for assessing the health-related quality of life (HRQoL) in women with cervical dysplasia. Our aim was to perform a cross-cultural adaptation and psychometric evaluation of the FACIT-CD scale in Serbian women with cervical squamous intraepithelial lesions (SIL).

Genome-wide DNA methylation profiles of porcine ovaries in estrus and proestrus.

DNA methylation is an important epigenetic modification involved in the estrous cycle and the regulation of reproduction. Here, we investigated the genome-wide profiles of DNA methylation in porcine proestrus and estrus ovaries using methylated DNA immunoprecipitation sequencing (MeDIP-seq). The results showed that DNA methylation was enriched in intergenic and intron regions. The methylation leve...

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