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Pallister-Killian syndrome (PKS) was first described by Pallister et al. in 1977 . This syndrome is the result of partial tetrasomy of the short arm of chromosome 12, but the mechanism that leads to the formation of isochromosome 12p in PKS is not clear. One of the possibilities is related to parent age, especially maternal age on the formation of isochromosome 12p in PKS . Prenatal diagnosis is u...
To achieve consensus on the minimum reporting set of study variables for fetal growth restriction (FGR) research studies. Determination of a list of variables considered essential to be reported independent of a specific hypothesis is likely to improve the study quality by inclusion of essential end-points, enhancing the consistency among studies and minimizing potential confounding. This in turn ...
The aim of this study was to perform a comprehensive assessment of the placental aging process through senescence and apoptotic markers in late-onset small fetuses classified as SGA or FGR.
Conjoined twins(CT) are a rare complication of monozygotic twinning(MT) in which one or more organs are joined in utero. Although the embryopathogenesis of these cases remains a lively focus of interest, the impact on the development of the umbilical cord(UC) and its vessels in CT remains still poorly investigated . This article is protected by copyright. All rights reserved.
To investigate the predictive value of delta middle cerebral artery - peak systolic velocity (MCA-PSV) > 0.5 multiples of the median (MoM) compared to cut-off MCA-PSV values (>1.5 MoM in the donor, < 1.0 MoM in the recipient) for the diagnosis of twin anemia polycythemia sequence (TAPS).
To examine the DV flow in fetuses with and without a cardiac defect. In addition to the standard assessment of the DV PIV and the a-wave, we evaluated different phases of the DV flow.
Norrie disease (ND; OMIM: 310600) is a rare, X-linked, recessive genetic disease caused by mutations in the NDP gene and characterized by congenital blindness due to bilateral degenerative changes in neuroretina. About half of ND patients have intellectual disability. ND first manifests by ocular features during the third trimester of pregnancy after normal scan findings of the first two trimester...
To report our experience with fetal diagnosis of right aortic arch (RAA) variants based on the ductus arteriosus (DA) anatomy and brachiocephalic vessel branching pattern (BVBP) respectively to the trachea and to establish whether the echocardiographic "V-shaped" or "U-shaped" appearances of the fetal upper mediastinum were sufficiently accurate for fetal aortic arch (AA) assessment.
To quantify the rate of perinatal mortality in monochorionic monoamniotic (MCMA) twin pregnancies according to gestational age and to ascertain the incidence of mortality in pregnancies managed as inpatient compared to outpatient.
Despite advances in antenatal care, fetal growth restriction (FGR) continues to contribute to excess perinatal mortality and morbidity. The literature has recently been enriched with several landmark studies on FGR, which will facilitate standardization of the diagnostic criteria, identification of the at-risk fetus, prenatal screening, candidate preventors and optimal management. However, these s...
Management of adnexal torsion in a dichorionic diamniotic pregnancy at 32 weeks is presented. Adnexal torsion is a rare condition in pregnancy, particularly during late third trimester and with normal ovary and tube. The size of a twin uterus at late third trimester prevented a laparoscopic approach. A longitudinal laparotomic incision below the umbilicus permitted detorsion and fixation of the ...
Acupuncture has been used for women during menopausal transition, but evidence is limited.
Steroidogenic activity in the equine ovary from birth to puberty has been poorly investigated. This study aimed to examine the capability of the ovarian follicles of prepubertal and pubertal fillies to produce steroid hormones and to evaluate the expression and cellular localization of androgen receptor (AR) in their ovaries. The ovaries of 6-18 month-old fillies were divided into two groups: prep...
Shoulder dystocia (SD) is an obstetric emergency which if not carefully diagnosed and managed, can contribute to lifelong neonatal morbidities. Despite current guidelines on the definition of SD (impaction of the fetal shoulder behind the maternal symphysis pubis and need for ancillary manoeuvres or head-body delivery interval (HBDI) >60 s) its accurate diagnosis requires clinical expertise as w...
To evaluate sentinel lymph node (SLN) mapping for endometrial cancer, using radioisotope and indocyanine green (ICG) injections.
To examine the demographic characteristics and mental health of women in rural Zambia who experienced physical intimate partner violence (IPV) postpartum.
To assess studies reporting reference ranges for Doppler indices of umbilical artery (UA), middle cerebral artery (MCA) and cerebroplacental ratio (CPR), using a set of predefined methodological quality criteria for study design, statistical analysis and reporting methods.
Ovarian cancer is a complicated malady associated with cancer stem cells (CSCs) contributing to 238,700 estimated new cases and 151,900 deaths per year, worldwide. CSCs comprise a tiny fraction of tumor-bulk responsible for cancer recurrence and eventual mortality. CSCs or tumor initiating cells are responsible for self-renewal, differentiation and proliferative potential, tumor initiation capabil...
Hyperemesis gravidarum, excessive vomiting in pregnancy, affects approximately 0.3-3.0% of all pregnancies, but the risk is considerably higher in pregnancies following a hyperemetic pregnancy. The reported recurrence rate of hyperemesis gravidarum is wide, ranging from 15% to 81%, depending on study settings. Factors affecting recurrence of hyperemesis gravidarum are as yet insufficiently studied...