Optometry Research

09:36 EST 19th February 2019 | BioPortfolio

Pentacam and vector analysis to evaluate longitudinal corneal tomographical changes in non-progressive keratoconus eyes.

Peripheral refraction and spherical aberration profiles with single vision, bifocal and multifocal soft contact lenses.

To compare the peripheral refraction and spherical aberration profiles along three visual field meridians of 16 commercial single vision (SV), bifocal (BF) and multifocal (MF) test contact lenses with a single vision control.

"Intraocular Oxygen and Antioxidant Status: New Insights on the Effect of Vitrectomy and Glaucoma Pathogenesis".

To investigate correlations of oxygen (pO) in the ocular anterior segment of human eyes and aqueous humor antioxidant levels of ascorbate (AsA) and total reactive antioxidant potential (TRAP) with glaucoma and vitreous status.

A machine learning model on orthokeratology lens fitting based on the data of optometry examination.

To get an orthokeratology lens fitting model according to the research of the optometry examination data, which can help to improve the work efficiency and increase the hitting rate of prescription. The relationship between the basic optometry examination data and the effective optometry prescription was evaluated. We got 1 467 sets of data, including 80%(1 173) for training and 20%(294) for test...

The effect of corneal biomechanical properties on opaque bubble layer in small incision lenticule extraction (SMILE).

To investigate the influence of corneal biomechanical properties on opaque bubble layer (OBL) in small incision lenticule extraction (SMILE). In this nested case control study, 20 patients (31 eyes) were enrolled in OBL group, while 51 patients (98 eyes) were included in non-OBL group. The parameters were obtained by Pentacam HR and Corvis ST examinations. Independent test was used to analyze th...

Clinical features, treatment distribution and outcomes of Mooren's ulcer.

To investigate the clinical features, treatment distribution and transition of Mooren's ulcer, and to observe the clinical outcomes and recurrence. Retrospective series case study. Medical records of 125 patients (154 eyes) with Mooren's ulcer treated between January 1996 and December 2015 at our hospital were retrospectively reviewed. Seventy-eight males and 47 females were include, with age of ...

Mucoadhesive olaminosomes: A novel prolonged release nanocarrier of agomelatine for the treatment of ocular hypertension.

Mucoadhesive olaminosomes are novel nanocarriers designed to control agomelatine release and enhance its bioavailability. Olaminosomes were prepared using oleic acid, oleylamine and sorbitan monooleate adopting thin film hydration technique. Chitosan HCl was added to impart the mucoadhesive properties to the olaminosomes. Mucoadhesive olaminosomes were characterized for their particle size, in-vit...

Categorization deficit of facially expressed anger in insomnia (Commentary on Zhang et al. Individuals with insomnia misrecognize angry faces as fearful faces while missing the eyes: an eye-tracking study).

A technical protocol for an experimental ex vivo model using arterially perfused porcine eyes.

Ex vivo ocular perfused models have been described in the past and were applied in different mammalian species as platforms to test drug delivery systems and surgical techniques. However, reproduction of those methods is challenging because extensive and precise description of the protocols used is lacking. In this technical paper we provide a detailed description of all the steps to be followed f...

Cataract Surgery: When the Eyes Are Bigger Than the Stomach.

Understanding Ocular Inflammation in Eyes Treated With Intravitreal Gene Therapy.

Balance control during stance - A comparison between horseback riding athletes and non-athletes.

Horseback riding requires the ability to adapt to changes in balance conditions, to maintain equilibrium on the horse and to prevent falls. Postural adaptation involves specific sensorimotor processes integrating visual information and somesthesic information. The objective of this study was to examine this multisensorial integration on postural control, especially the use of visual and plantar in...

Distinguishing Highly Asymmetric Keratoconus Eyes Using Dual Scheimpflug/Placido Analysis.

To identify the best metrics or combination of metrics that provide the highest predictive power between normal eyes and the clinically unaffected eye of patients with highly asymmetric keratoconus using data from a Dual Scheimpflug/Placido device DESIGN: Retrospective case-control study.

Rates of Ganglion Cell-Inner Plexiform Layer Thinning in Normal, Open-Angle Glaucoma and Pseudoexfoliation Glaucoma Eyes: A Trend-Based Analysis.

The purpose of this study was to determine the rate of ganglion cell-inner plexiform layer (GCIPL) thinning by Cirrus high-definition optical coherence tomography (HD-OCT) in normal eyes and open-angle glaucoma (OAG) and pseudoexfoliation glaucoma (PXG) eyes.

Gaze cues of isolated eyes facilitate the encoding and further processing of objects in 4-month-old infants.

We investigated young infants' object encoding and processing in response to isolated eye gaze cues on the neural and behavioral level. In two experiments, 4-month-old infants watched a pair of isolated eyes gazing towards or away from novel objects. Subsequently, the same objects were presented alone (i.e., without eyes). We measured event-related potentials (ERP) in response to object-directed a...

A pilot prospective study of 577-nm yellow subthreshold micropulse laser treatment with two different power settings for acute central serous chorioretinopathy.

To compare the efficacy of 50% threshold power with 25% threshold power of 577-nm subthreshold micropulse laser (SMPL) for acute central serous chorioretinopathy (CSC). Prospective, interventional, non-randomized, comparative case series. A total of 54 patients (54 eyes) with acute CSC were enrolled. Twenty-four eyes received 25% threshold power and 30 eyes received 50% threshold power of 577-nm S...

The Human Ocular Surface Fungal Microbiome.

To enumerate the ocular surface fungal microbiome of healthy human eyes by using next-generation sequencing (NGS).

Alpha -adrenoceptor agonists inhibit form-deprivation myopia in the chick.

The putative myopia-controlling receptor is thought to be muscarinic acetylcholine receptor subtype M , because mamba toxin-3 can inhibit form-deprivation myopia in chicks at a far lower concentration than atropine. However, mamba toxin-3 is equally potent at the human α -, α -, and α -adrenoceptors. To test the hypothesis that α-adrenoceptors might be involved in regulation of eye growth, the...

Understanding quality of life impact in people with retinal vein occlusion: a qualitative inquiry.

Although being the second most common sight-threatening retinal vascular disease after diabetic retinopathy, the patient-centred impact of retinal vein occlusion has not been well studied. This study aims to understand the quality of life issues in people with retinal vein occlusion using a qualitative methodology.

Attention to the face is characterised by a difficult to inhibit first fixation to the eyes.

The eyes are preferentially attended over other facial features and recent evidence suggests this bias is difficult to suppress. To further examine the automatic and volitional nature of this bias for eye information, we used a novel prompting face recognition paradigm in 41 adults and measured the location of their first fixations, overall dwell time and behavioural responses. First, patterns of ...

Spontaneous eye movements during focused-attention mindfulness meditation.

Oculometric measures have been proven to be useful markers of mind-wandering during visual tasks such as reading. However, little is known about ocular activity during mindfulness meditation, a mental practice naturally involving mind-wandering episodes. In order to explore this issue, we extracted closed-eyes ocular movement measurements via a covert technique (EEG recordings) from expert meditat...

Shorter sleep durations in adolescents reduce power density in a wide range of waking electroencephalogram frequencies.

Despite sleep's recognized biological importance, it has been remarkably difficult to demonstrate changes in brain physiology with reduced sleep durations. In a study of adolescents, we varied sleep durations by restricting time in bed for four nights of either 10, 8.5 or 7 h. Shorter sleep durations significantly decreased waking electroencephalogram (EEG) power in a wide range of frequencies wit...


The objective of this study was to assess the radiation doses received by anaesthetists from prostatic artery embolization (PAE) procedures. Ten PAE procedures conducted in a reference hospital in the city of Recife, Brazil were investigated. Occupational dosimetry was performed using thermoluminescent dosemeters which were located next to the eyes, close to the thyroid (over the shielding), on th...

Post-LASIK Ectasia: Twenty Years of a Conundrum.

Corneal ectasia has emerged as a serious complication of laser vision correction (LVC) procedures since the first report by Seiler in 1998. Thereby, its prevention has become a major concern for refractive surgeons. Ectasia occurs due to biomechanical decompensation of the stroma, which may be related to a severe impact on corneal structure (i.e., attempted treatment for high myopia) or the altere...

Extended (≥q12 Weeks) Dosing Interval With Intravitreal Aflibercept and Ranibizumab in Neovascular AMD: Post Hoc Analysis of VIEW Trials.

To evaluate outcomes and disease characteristics in eyes with neovascular age-related macular degeneration that received intravitreal aflibercept injection (IAI) and ranibizumab ≥q12 or

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