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Pancreatitis can affect both the exocrine and endocrine functions of the pancreas. Pancreatic acinar cells secrete bicarbonate and digestive enzymes into ducts that connect the pancreas to the duodenum at the ampulla of Vater (exocrine function). Pancreatic β-cells secrete insulin directly into the bloodstream (endocrine function).
Adapted from - http://www.merckmanuals.com/