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Patient Monitoring Research

09:47 EDT 19th August 2018 | BioPortfolio

Fluorescence based Nano Oxygen Particle (FNOP) for Spatiometric Monitoring of Cell Physiological Conditions.

Closed-loop artificial pancreas systems have recently been proposed as a solution for treating stage I diabetes by reproducing the function of the pancreas. However, there are many unresolved issues associated with their development, including monitoring and controlling oxygen, immune responses and the optimization of glucose. All of which need to be monitored and controlled to produce an efficien...

Monitoring of Hydrogenation by Benchtop NMR with Parahydrogen-Induced Polarization.

Reaction monitoring using nuclear magnetic resonance (NMR) spectroscopy is a powerful tool that provides detailed information on the characteristics and mechanism of the reaction. Although high-field NMR provides more accurate and abundant data, which can be explained in terms of Boltzmann factors, benchtop NMR is commonly used because of its low cost and simple maintenance. Therefore, hyperpolari...

Liquid biopsies for management of pancreatic cancer.

Pancreatic cancer is one of the main causes of cancer related deaths worldwide. It is asymptomatic at an early stage, and most diagnosis occurs when the disease is already at a late stage, by which time the tumor is nonresectable. In order to increase the overall survival of patients with pancreatic cancer, as well as to decrease the cancer burden, it is necessary to perform early diagnosis, progn...

Circulating APP, NCAM and Aβ serve as biomarkers for Alzheimer's disease.

Alzheimer's disease (AD) is the most common neurodegenerative disease and the early diagnosis and intervention are important for valid treatment of AD. However, there are few biomarkers for the diagnosis and monitoring of AD. In the present study, circulating APP, NCAM, Aβ40, and Aβ42 were measured in order to identify which marker or combination of markers could be useful, cost-effective and no...

Rheumatoid Arthritis-Associated Orbital Vasculitis.

A patient with a history of rheumatoid arthritis presented with bilateral orbital lesions while on abatacept. Biopsy of the lesions yielded pathologic assessment showing vasculitis with a mixed inflammatory infiltrate notable for numerous eosinophils. Despite initial improvement on cyclophosphamide therapy, she developed progression of the orbital lesions and lesions elsewhere on her body. All ser...

A novel minimally-occlusive cuff method utilizing ultrasound vascular imaging for stress-free blood pressure measurement: a-proof-of-concept study.

Occlusive cuff inflation in ambulatory blood pressure (BP) monitoring disturbs the daily life of the user, and affects efficacy of monitoring. To overcome this limitation, we have developed a novel minimally-occlusive cuff method for stress-free measurement of BP. This study aimed to experimentally evaluate the reliability of this method. Methods In this method, a thin-plate-type ultrasound probe ...

Generation of patient-specific cardiac vascular networks: a hybrid image-based and synthetic geometric model.

In this paper, we propose an algorithm for the generation of a patient-specific cardiac vascular network starting from segmented epicardial vessels down to the arterioles.

Monitoring of Metabolic, Cardiac, and Endocrine Indicators in Youth Treated With Antipsychotics as Reported by Health Care Professionals.

It is unclear how youth treated with antipsychotics are monitored. The purpose of this study was to assess monitoring of metabolic, cardiac, and endocrine indicators in youth (

CORR Insights®: Patient Perceptions Correlate Weakly With Observed Patient Involvement in Decision-making in Orthopaedic Surgery.

Simultaneous ultraperformance liquid chromatography/tandem mass spectrometry determination of four antihypertensive drugs in human plasma using hydrophilic-lipophilic balanced reversed phase sorbents sample preparation protocol.

Therapeutic drug monitoring of angiotensin converting enzyme inhibitors (ACEI) has a great impact in blood pressure control in patient with heart failure, hepatic and renal impairment. To provide an efficient tool for drug assessment in plasma, UPLC-MS/MS method was developed for simultaneous determination of benazepril hydrochloride (BNZ), fosinopril sodium (FOS), captopril (CAP) and hydrochlorot...

Exploring patients' and healthcare professionals' experiences of patient-witnessed resuscitation: a qualitative study protocol.

To explore the experiences of patients and healthcare professionals regarding patients witnessing resuscitation on another patient in hospital clinical wards.

Patient safety culture in a university hospital.

to assess patient safety culture in a university hospital.

SERS-based Quantification of Biomarker Expression at the Single Cell Level Enabled by Gold Nanostars and Truncated Aptamers.

Surface-enhanced Raman spectroscopy (SERS)-based biosensors have been used increasingly over the past few years for cancer detection and diagnosis. SERS-based imaging offers excellent sensitivity and has advantages over other detection techniques such as fluorescence. In this study, we developed a novel biosensor to detect the cancer biomarker epithelial cell adhesion molecule (EpCAM) and quantify...

Root Cause Analysis of Oncology Adverse Events in the Veterans Health Administration.

Oncology providers are leaders in patient safety. Despite their efforts, oncology-related medical errors still occur, sometimes resulting in patient injury or death. The Veterans Health Administration (VHA) National Center of Patient Safety used data obtained from root cause analysis (RCA) to determine how and why these adverse events occurred in the VHA, and how to prevent future reoccurrence. Th...

Development of low-cost non-contact structural health monitoring system for rotating machinery.

Condition monitoring systems are increasingly being employed in industrial applications to improve the availability of equipment to increase the overall equipment efficiency. Condition monitoring of gearboxes, a key element of rotating machines, ensures to continuously reduce and eliminate costs, unscheduled downtime and unexpected breakdowns. This study demonstrates a low-cost microcontroller-bas...

Analysing the effect of paddy rice variety on fluorescence characteristics for nitrogen application monitoring.

Paddy rice is one of the most important cereal crops worldwide, so it is very important to accurately monitor its growth status and photosynthetic efficiency. The nitrogen (N) level is a key factor closely related to crop growth. In this study, laser-induced fluorescence (LIF) technology combined with multi-variate analysis was applied to investigate the effect of paddy rice variety on N fertilize...

The Patient as Reformation - Here We Stand Part Three - Legitimate Authority and True Reform.

Healthcare delivery in the U.S is in the midst of a social crisis and demands social reform. Physician-reformers must understand that the roots of this dilemma lie in a loss of legitimate authority, as it extends to the patient. Legitimate authority in medicine exists when patient-centeredness leads - with self-less advocacy that strengthens the patient bond, radical accountability that restores t...

21 Century Citizen Pharma: The FDA & Patient-Focused Product Development.

Perpetual debate regarding the delicate balance between access and innovation and the protection of the public health and safety dominate discussions of the United States Food and Drug Administration ("FDA"). Established chiefly as a command and control federal administrative agency, iterative changes in legislation have shaped the FDA's activity in drug, biologic, and medical device regulation ov...

Iterative Design of Visual Analytics for a Clinician-in-the-loop Smart Home.

In order to meet the health needs of the coming "age wave", technology needs to be designed that supports remote health monitoring and assessment. In this study we design CIL, a clinician-in-the-loop visual interface, that provides clinicians with patient behavior patterns, derived from smart home data. A total of 60 experienced nurses participated in an iterative design of an interactive graphica...

Clinical outcomes with therapeutic drug monitoring in inflammatory bowel disease: A systematic review with meta-analysis.

We undertook a systematic review and meta-analysis examining the effectiveness of therapeutic drug monitoring (TDM) to improve clinical outcomes in anti-TNF-treated IBD patients.

Is HIV patient navigation associated with HIV care continuum outcomes? A systematic review.

To provide the first systematic review on the associations between HIV patient navigation and HIV care continuum outcomes (i.e., linkage to care, retention in care, ART uptake, medication adherence, and viral suppression) in the United States (U.S.). We identified primary research studies that addressed these associations and qualitatively assessed whether provision of patient navigation was posit...

ERP indices of performance monitoring and feedback processing in psychosis: A meta-analysis.

Although individuals with, or at risk for, psychotic disorders often show difficulties with performance monitoring and feedback processing, findings from studies using event-related potentials (ERPs) to index these processes are not consistent. This meta-analytic review focused on studies of two different indexes of performance monitoring, the early error-related negativity (ERN; n = 25) and t...

The clinical relevance of laryngopharyngeal reflux monitoring is poor.

Monitoring bone changes due to calcium, magnesium, and phosphorus loss in rat femurs using Quantitative Ultrasound.

Bone mineral density is an important parameter for the diagnosis of bone diseases, as well as for predicting fractures and treatment monitoring. Thus, the aim of the present study was to evaluate the potential of Quantitative Ultrasound (QUS) to monitor bone changes after calcium, phosphorus, and magnesium loss in rat femurs in vitro during a demineralization process. Four quantitative ultrasound ...

The Association of Anesthesia Clinical Directors (AACD) Glossary of Times Used for Scheduling and Monitoring of Diagnostic and Therapeutic Procedures.

The Glossary of Times Used for Scheduling and Monitoring of Diagnostic and Therapeutic Procedures also known as the Procedural Times Glossary (PTG) was originally developed with the support of the Association of Anesthesia Clinical Directors (AACD). The goal was to establish standardized terms to measure and assess the performance of operating room and procedural areas. By incorporating standardiz...

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