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Pediatrics Research

04:36 EDT 17th October 2018 | BioPortfolio

Phosphorylation of SRSF1 at Tyr-19 promotes cell proliferation in pediatric acute lymphoblastic leukemia.

Serine/arginine-rich splicing factor 1 (SRSF1) has been linked to various human cancers including pediatric acute lymphoblastic leukemia (ALL). Our previous study has shown that SRSF1 potentially contributes to leukemogenesis, however its underlying mechanism remains unclear. In this study, leukemic cells were isolated from pediatric ALL bone marrow samples, followed by immune-precipitation assays...

Retrospective Analysis of Simple and Stage II Renal Cysts: Pediatric Nephrology Point of View.

Increased ultrasonography (US) use has been correlated with an increased incidence of pediatric renal cysts. For simple and stage II cysts, the malignancy risk is low in adulthood, no follow-up is recommended; but there is no consensus on childhood management. Since pediatric renal cysts may be manifestations of hereditary cystic diseases, a different approach and follow-up should be taken for the...

The Association Between Maternal Factors and Preadolescent Breakfast Skipping: The Mediating Role of Preadolescent Attitudes Toward Breakfast.

Although skipping breakfast is common among children and adolescents, daily breakfast consumption is a healthy habit that is particularly important in childhood. There is a link between children's attitudes toward breakfast, breakfast-skipping behaviors, and maternal factors. Evidence demonstrating a clear relationship between maternal factors and preadolescent attitudes and behaviors toward break...

Hypo and hypercalcemia: from diagnosis to treatment.

Emergencies in pediatric dentistry are a real challenge for any healthcare professional. As pediatric dentists, we are aware that this practitioner has to manage an emotional situation, often the first contact of a young child with dentistry, with sometimes complex clinical circumstances. This review of the different emergency pathologies presents the characteristics, the diagnoses and treatments,...

Longitudinal linkages between parenting stress and oppositional defiant disorder (ODD) symptoms among Chinese children with ODD.

Parents of children with oppositional defiant disorder (ODD) experience considerable stress and challenges in parenting. Based on a 2-year, 3-wave longitudinal study of children with ODD (N = 243, mean age = 9.47 years, SD = 1.53; 72.8% boys) and their parents in Mainland China, our study examined the relation between 3 dimensions of parenting stress (i.e., Parental Distress, Parent-Child Dysfunct...

Adult attachment representations and the quality of romantic and parent-child relationships: An examination of the contributions of coherence of discourse and secure base script knowledge.

Attachment theory suggests that early experiences with caregivers are carried forward across development in the form of mental representations of attachment experiences. Researchers have investigated at least two representation-based constructs when studying attachment and successful adaptation in adulthood: (a) coherence of autobiographical discourse/memories and (b) knowledge of the secure base ...

Performance and Symptom Validity Testing in Pediatric Assessment: A Review of the Literature.

There has been an increased recognition that validity testing is an integral component of evaluations conducted with youth. The incorporation of validity testing provides an objective basis for placing confidence in the test data as an accurate assessment of the child's or adolescent's current ability level and/or an accurate indication of the child's or adolescent's current symptoms or behavioral...

Predictors of Cognitive and Academic Outcome following Childhood Subcortical Stroke.

Childhood arterial ischemic stroke often involves basal ganglia and thalamus but little is known about neuropsychological outcomes in this group. We examined intellectual ability, academics, attention, executive function, and psychological diagnoses in children and adolescents (6-20 years of age) with childhood stroke involving the basal ganglia (n = 32) or thalamus (n = 12). Intellectual abi...

Moving towards Therapists Becoming Better Educators: A Commentary on Changes in the Content of Pediatric Physical Therapy for Infants: A Quantitative, Observational Study.

Patients and their families have expressed that they want information (Hendricks, 2000) and as a result often turn to Google for health and medical information. Society as a whole is more informed than ever and no longer rely only on medical practitioners as in previous generations. Instead, and rightly so, they question medical experts and want to know the reasoning and rationale behind everythin...

Alexithymia, Impulsivity, and Reward Sensitivity in Young Adult University Student Children of Alcoholics.

Personality traits previously known as risk factors for alcohol use disorder (AUD) were assessed in 29 young adult children of alcoholics (COAs) and 68 young adult children of nonalcoholics (non-COAs). Male and female university students (M = 22.11 years) completed questions pertaining to demographics and alcohol use, and the Children of Alcoholics Screening Test; Toronto Alexithymia Scale; ...

Emotion Reactivity and Regulation in Adolescent Girls Following an Interpersonal Rejection.

Failures in emotion regulation, especially as a result of interpersonal stress, are implicated as transdiagnostic risk factors for psychopathology. This study examines the effects of an experimentally timed targeted interpersonal rejection on emotion reactivity and regulation in typically developing adolescent girls. Girls ( N = 33, ages 9-16 years, M = 12.47, SD = 2.20) underwent fMRI involving a...

Predicting Physical Activity Among Children: Investigating Interaction Effects in the Theory of Planned Behavior.

The theory of planned behavior (TPB) has been criticized for not including interactions between the variables assumed to predict behavior. This study sought to test how TPB variables interact to predict physical activity (PA) in children.

Children's Other-Oriented Behaviors in Distress Situations.

Children's other-oriented behaviors in distress situations, when observed, appear to be different depending on the kind of distress situations. The authors investigated developmental differences in children's other-oriented behaviors by comparing two distress situations: participant-caused/other-victim and other-caused/participant-victim situations. The kinds of other-oriented behaviors younger an...

Pediatric integrated behavioral health service delivery models: Using a federal framework to assess levels of integration.

To assess the level of integration of pediatric integrated behavioral health service delivery models (IBHSDM) since it has not been well established.

Six minute walk distance and reference values in healthy Italian children: A cross-sectional study.

The 6-minute walking test (6MWT) is a simple assessment tool to evaluate exercise capacity. The result of the test is the distance that a subject can walk at a constant and normal pace within 6 minutes (6MWD) and reflects the aerobic/fitness performance related to walking function. Use of 6MWT has been relevant to assess exercise tolerance either in healthy children or in patients with, heart, lun...

Epidemiology, clinical presentation and respiratory sequelae of adenovirus pneumonia in children in Kuala Lumpur, Malaysia.

To describe the severity, human adenovirus (HAdV) type and respiratory morbidity following adenovirus pneumonia in children.

Reported prevalence of childhood maltreatment among Chinese college students: A systematic review and meta-analysis.

To estimate the prevalence of childhood maltreatment among college students in China by a systematic review and meta-analysis.

Comment on "Maternal employment in low- and middle-income countries is associated with improved infant and young child feeding".

Childhood BMI is inversely associated with pubertal timing in normal-weight but not overweight boys.

An inverse association between childhood body mass index (BMI; in kg/m2) and pubertal timing is well established for girls. Among boys, studies are scarce and the results inconclusive.

The Persistent Signal from Television Viewing in Childhood on Overweight and Obesity Throughout the Life Course.

Few studies address the association between television (TV) viewing in childhood and overweight/obesity across the life course. Among 30,921 mother-daughter dyads from the Nurses' Mothers' Cohort (2001) and the Nurses' Health Study II (1989 and 1991), the following information was collected: daughter's TV viewing and physical activity (PA) at ages 3─5 and 5─10, somatotype at ages 5 and 10, and...

Congenital Oculonasal Synkinesis: Botulinum Toxin A in the Treatment of a Pure Facial Synkinesis.

Parent-mediated interventions for promoting communication and language development in young children with Down syndrome.

Communication and language development are areas of particular weakness for young children with Down syndrome. Caregivers' interaction with children influences language development, so many early interventions involve training parents how best to respond to their children and provide appropriate language stimulation. Thus, these interventions are mediated through parents, who in turn are trained a...

Comparison of echocardiography and 64-slice spiral computed tomography in the diagnosis of congenital heart disease in children.

The diagnosis of congenital heart disease in children has been an issue in the medical community. Timely diagnosis and treatment can provide a greater guarantee for children's healthy growth. In recent years, there have been more and more studies on the diagnosis of congenital heart disease in children. This paper compares the advantages and disadvantages of echocardiography and 64-slice spiral co...

Coverage and educational actions related to the national vitamin A supplementation program: a study in children from the state of Alagoas.

To estimate the coverage of the National Vitamin A Supplementation Program (Programa Nacional de Suplementação de Vitamina A) in children from Alagoas, to identify factors associated with this coverage, and to analyze the adequacy of nutrition education actions.

Clinically Diagnosing Pertussis-Associated Cough in Adults and Children: Chest Guideline and Expert Panel Report.

The decision to treat a suspected case of pertussis with antibiotics is usually based on a clinical diagnosis rather than waiting for laboratory confirmation. The current guideline focuses on making the clinical diagnosis of pertussis-associated cough in adults and children.

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