Pneumonia Research

09:36 EDT 21st March 2019 | BioPortfolio

A case of Pneumocystis pneumonia, with a granulomatous response and Vitamin D-mediated hypercalcemia, presenting 13 years after renal transplantation.

Vitamin D-mediated hypercalcemia is an uncommon complication of Pneumocystis infection. A granulomatous response resulting from Pneumocystis infection is also atypical. In this report, we describe an exceptional case of granulomatous Pneumocystis pneumonia associated with vitamin D-mediated hypercalcemia, in a patient who presented unusually late after renal transplantation. The patient's hypercal...

Effect of using frozen-thawed bovine semen contaminated with lumpy skin disease virus on in vitro embryo production.

Lumpy skin disease (LSD) is an important transboundary animal disease (TAD) of cattle with significant economic impact because of the implications for international trade in live animals and animal products. LSD is caused by a Capripoxvirus, lumpy skin disease virus (LSDV), and results in extensive hide and udder damage, fever and pneumonia. LSDV can be shed in semen of infected bulls for prolonge...

Cardiovascular sequelae of pneumonia.

In this brief review, we discuss the current epidemiological data and latest results from basic research on the cardiovascular sequelae after lower respiratory tract infection.

Group B Streptococcus early-onset disease and observation of well-appearing newborns.

International guidelines lack a substantial consensus regarding management of asymptomatic full-term and late preterm neonates at risk for early-onset disease (EOS). Large cohorts of newborns are suitable to increase the understanding of the safety and efficacy of a given strategy.

Yield performance of early-season rice cultivars grown in the late season of double-season crop production under machine-transplanted conditions.

In order to solve the problem of labor shortage in double-season rice production areas, machine transplanting, as opposed to manual transplanting, has become the more popular alternative method in rice cultivation. However, the most existing late rice cultivars are not suitable for machine double-season rice cultivation due to their long duration of growth. Therefore, based on the previous studies...

Incidence of community acquired pneumonia in children aged 2-59 months of age in Uttar Pradesh and Bihar, India, in 2016: An indirect estimation.

Community Acquired Pneumonia (CAP) is the leading cause of mortality in children younger than five years of age in developing countries, including India. Hence, this prospective study was performed to estimate the incidence of CAP in children (2-59 months)in four districts of Northern India.

Omadacycline: A novel tetracycline derivative with oral and intravenous formulations.

Omadacycline, an aminomethylcycline, is a novel member of the tetracycline class of antibiotics. It has received approval by the U.S. Food and Drug Administration (FDA) for treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSIs) and is available in both oral and intravenous formulations. It is also being evaluated in clinical tria...

Development of attenuated erythromycin-resistant Streptococcus agalactiae vaccine for tilapia (Oreochromis niloticus) culture.

Streptococcus agalactiae is an important pathogen in fish, causing great losses of intensive tilapia farming. To develop a potential live attenuated vaccine, a re-attenuated S. agalactiae (named TFJ-ery) was developed from a natural low-virulence S. agalactiae strain TFJ0901 through selection of resistance to erythromycin. The biological characteristics, virulence, stability and the immunization...

Spectral properties of Tm3+ doped NaYF4 up-converting nanoparticles under single and double photoexcitation wavelengths.

As soon as excited long-living levels of lanthanides become populated, numerous novel photoexcitation schemes may become available. It paves the way to numerous new possibilities or applications, such as up-conversion (UC) enhancement or intentional depletion towards stimulated emission depletion microscopy (STED). However, this type of studies requires the possibility of performing power dependen...

A Novel Double-Blind, Placebo-Controlled Food Challenge Matrix for Milk and Raw Egg.

The double-blind, placebo-controlled food challenge (DBPCFC) is still considered to be the gold standard in food allergy diagnosis. This test is however not common practice in routine due to several practical limitations, especially for non-IgE-mediated food allergy with its typical delayed food allergic reactions.

Neurodegenerative Diseases and Ageing.

This chapter describes the main neuropathological features of the most common age associated neurodegenerative diseases including Alzheimer's disease, Lewy body diseases, vascular dementia and the various types of frontotemporal lobar degeneration. In addition, the more recent concepts of primary age-related tauopathy and ageing-related tau astrogliopathy as well as chronic traumatic encephalopath...

Isolated Cystic Lung Disease: An Algorithmic Approach to Distinguishing Birt-Hogg-Dubé Syndrome, Lymphangioleiomyomatosis, and Lymphocytic Interstitial Pneumonia.

Birt-Hogg-Dubé (BHD) syndrome, lymphangioleiomyomatosis (LAM), and lymphocytic interstitial pneumonia (LIP) frequently present as isolated cystic lung disease and can be challenging to distinguish. If imaging findings are otherwise unremarkable, the radiologist is unaided by ancillary CT findings in narrowing the diagnosis. We hypothesized that the distribution and morphologic features of lung cy...

Re: Association of the Hospital Readmissions Reduction Program with Mortality among Medicare Beneficiaries Hospitalized for Heart Failure, Acute Myocardial Infarction, and Pneumonia.

A Randomized Double-blind Clinical Trial of Dentin Surface Treatments for Composite Restorations in Noncarious Cervical Lesions: A 36-month Evaluation.

This randomized, double-blind clinical trial aimed to evaluate the influence of different dentin surface treatments in noncarious cervical lesions (NCCLs).

Effectiveness and safety of perioperative enteral feeding in patients with burn injuries: a systematic review protocol.

The question of this review is: What is the effectiveness and safety of perioperative enteral nutrition in patients with burn injuries?More specifically, this systematic review will aim to determine whether short fasting (nasogastric feeding up to two hours prior to theater and immediately thereafter) or nil fasting (nasogastric feeding in ventilated patients or post-pyloric feeding in non-ventila...

Neutrophil-to-lymphocyte ratio as a serum biomarker associated with community acquired pneumonia

Community acquired pneumonia (CAP) is the main infectious cause of mortality in the world. Several scales evaluates outcomes, however the current tendency favors using biomarkers as surrogates of clinical prognosis.

Causative Pathogens of Endophthalmitis after Intravitreal Anti-VEGF Injection: An International Multicenter Study.

The main objective of this study was to investigate the microbiological spectrum of endophthalmitis after anti-VEGF injections and to compare streptococcal with non-streptococcus-associated cases with regard to baseline characteristics and injection procedure.

A case of lipid pneumonia induced by gasoline aspiration.

Clinical analysis of infective endocarditis with septic pulmonary embolism.

To analyze the clinical features of infective endocarditis with septic pulmonary embolism, and to improve the diagnosis and treatment of the disease. Retrospective analysis of clinical manifestations, blood culture, echocardiography, chest CT and diagnosis and treatment of 16 patients with infective endocarditis and septic pulmonary embolism in the First Affiliated Hospital of Zhengzhou Universit...

Applications of CRISPR systems in respiratory health: Entering a new 'red pen' era in genome editing.

Respiratory diseases, such as influenza infection, acute tracheal bronchitis, pneumonia, tuberculosis, chronic obstructive pulmonary disease, asthma, lung cancer and nasopharyngeal carcinoma, continue to significantly impact human health. Diseases of the lung and respiratory tract are influenced by environmental conditions and socio-economic factors; however, many of these serious respiratory diso...

Luminescent CeO:Eu nanocrystals for robust in situ HO real-time detection in bacterial cell cultures.

Hydrogen peroxide (HO) quantification in biomedicine is valuable as inflammation biomarker but also in assays employing enzymes that generate or consume HO linked to a specific biomarker. Optical HO detection is typically performed through peroxidase-coupled reactions utilizing organic dyes that suffer, however, from poor stability/reproducibility and also cannot be employed in situ in dynamic com...

The multifactorial etiology of stroke-associated pneumonia.

Glycyrrhizin administration ameliorates Streptococcus aureus-induced acute lung injury.

Streptococcus aureus (S. aureus)-induced acute lung injury (ALI) has a high incidence of mortality clinically. Glycyrrhizin (GL) is a traditional Chinese medicine for anti-inflammatory. However, the role of GL in S. aureus-induced ALI has not previously been elucidated. GL (25 mg/kg i.p.) administration exerts potent anti-inflammatory effect in this model. GL administration significantly allev...

Contribution of NDH-dependent cyclic electron transport around photosystem I to the generation of proton motive force in the weak mutant allele of pgr5.

In angiosperms, cyclic electron transport (CET) around photosystem I (PSI) consists of two pathways, depending on PGR5/PGRL1 proteins and the chloroplast NDH complex. In single mutants defective in chloroplast NDH, photosynthetic electron transport is only slightly affected at low light intensity, but in double mutants impaired in both CET pathways photosynthesis and plant growth are severely affe...

Evaluation of the ratio of the estimated area under the concentration-time curve to minimum inhibitory concentration (estimated AUIC) as a predictor of the outcome for tigecycline treatment for pneumonia due to multidrug-resistant bacteria in an intensive care unit.

Based on pharmacokinetics/pharmacodynamics (PK/PD) and the minimum inhibitory concentration (MIC) of tigecycline (TGC), dose increases have been advocated to maximize the efficacy against pneumonia that is suspected to be due to multidrug-resistant (MDR) bacteria in an intensive care unit. This practice-based study explored the relationship between the predicted PK parameter, the ratio of the area...

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