Advertisement

Topics

Sulfamethoxazole and Trimethoprim Tablets USP | Sulfamethoxazole and Trimethoprim

04:35 EDT 27th August 2014 | BioPortfolio

Note: While we endeavour to keep our records up-to-date one should not rely on these details being accurate without first consulting a professional. Click here to read our full medical disclaimer.

Inactive Ingredients: Docusate sodium, magnesium stearate, pregelatinized starch, sodium benzoate, and sodium starch glycolate.

IMAGE sulfatrime-str1.jpgIMAGE sulfatrime-str2.jpg
a. These interpretative standards are applicable only to broth microdilution 
    susceptibility tests with Haemophilus influenzae using Haemophilus Test
    Medium (HTM)4.
b. These interpretative standards are applicable only to broth microdilution 
    susceptibility tests using cation-adjusted Mueller-Hinton broth with 2% to 5%
    lysed horse blood4.
   For testing Enterobacteriaceae:
MIC (mcg/mL)
Interpretation
≤2/38
Susceptible (S)
≥4/76
Resistant (R)
   When testing either Haemophilus influenzae a or
   Streptococcus pneumoniae b:
MIC (mcg/mL)
Interpretationb
≤0.5/9.5
Susceptible (S)
1/19-2/38
Intermediate (I)
≥4/76
Resistant (R)
Microorganism MIC (mcg/mL)
c. This quality control range is applicable only to Haemophilus influenzae ATCC 49247
    tested by broth microdilution procedure using Haemophilus Test Medium (HTM) 4.
d. This quality control range is applicable to tests performed by the broth microdilution
     method only using cation-adjusted Mueller-Hinton broth with 2% to 5% lysed horse blood4.
   Escherichia coli                                    ATCC 25922
≤0.5/9.5
   Haemophilus influenzae c                             ATCC 49247
0.03/0.59 – 0.25/4.75
   Streptococcus pneumoniae d                       ATCC 49619
0.12/2.4 – 1/19
For testing either Enterobacteriaceae or Haemophilus influenzae e:
e. These zone diameter standards are applicable only for disk diffusion
   testing with Haemophilus influenzae and Haemophilus Test Medium (HTM)5.
Zone Diameter (mm)
Interpretation
≥16
Susceptible (S)
11 – 15
Intermediate (I)
≤10
Resistant (R)
When testing Streptococcus pneumoniae f:
f. These zone diameter interpretative standards are applicable only to tests
   performed using Mueller-Hinton agar supplemented with 5% defibrinated
   sheep blood when incubated in 5% CO2 5.
Zone Diameter (mm)
Interpretation
≥19
Susceptible (S)
16 – 18
Intermediate (I)
≤15
Resistant (R)
Microorganism Zone Diameter Ranges
(mm)
g. This quality control range is applicable only to Haemophilus influenzae ATCC 49247
    tested by a disk diffusion procedure using Haemophilus Test Medium (HTM)5.
h. This quality control range is applicable only to tests performed by disk diffusion using
    Mueller-Hinton agar supplemented with 5% defibrinated sheep blood when incubated
    in 5% CO2 5.
   Escherichia coli                          ATCC 25922
24-32
   Haemophilus influenzae g               ATCC 49247
24-32
   Streptococcus pneumoniae h        ATCC 49619
20-28
Children 2 months of age or older:
      Weight          Dose–every 12 hours   
      lb             kg       Tablets
22
10

44
20
1
66
30

88
40
2 or 1 DS tablet
   Creatinine Clearance   
(mL/min)
Recommended
Dosage Regimen
Above 30
   Usual standard regimen   
15-30
½ the usual regimen
Below 15
Use not recommended
      Weight          Dose-every 6 hours   
      lb             kg       Tablets
18
8

35
16
1
53
24
1½   
70
32
2 or 1 DS tablet
88
40
2½ 
106
48
3 or 1½  DS tablets
141
64
4 or 2 DS tablets
176
80
5 or 2½ DS tablets
   Body Surface Area       Dose-every 12 hours   
(m2) Tablets
0.26
-
0.53
½
1.06
1
IMAGE sulfatrime-fig1.jpgIMAGE sulfatrime-fig2.jpg

Manufacturer

Aurobindo Pharma Limited

Active Ingredients

Source

Drugs and Medications [129 Associated Drugs and Medications listed on BioPortfolio]

Sulfamethoxazole and trimethoprim [Teva Parenteral Medicines, Inc]

Sulfamethoxazole and Trimethoprim Injection, USP

Sulfamethoxazole and trimethoprim [Aurobindo Pharma Limited]

Sulfamethoxazole and Trimethoprim Oral Suspension, USP

Sulfamethoxazole and trimethoprim [Aurobindo Pharma Limited]

Sulfamethoxazole and Trimethoprim Tablets, USP

Sulfamethoxazole and trimethoprim oral suspension usp form no. 1284/1285 rev. 3/06 vc2785 [Actavis Mid Atlantic LLC]

SULFAMETHOXAZOLE AND TRIMETHOPRIM ORAL SUSPENSION USP FORM NO. 1284/1285 Rev. 3/06 VC2785

Sulfamethoxazole and trimethoprim [Physicians Total Care, Inc.]

Sulfamethoxazole and Trimethoprim Tablets, USP

Clinical Trials [78 Associated Clinical Trials listed on BioPortfolio]

Prophylactic Trimethoprim/Sulfamethoxazole to Prevent Severe Infections in Patients With Lupus Erythematous

The purpose of this study is to determine whether trimethoprim/sulfamethoxazole is effective in preventing serious infectious complications (those that require hospitalization or lead to d...

A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome

The primary objective of the study is to evaluate the effectiveness of l-leucovorin in preventing toxicity from high dose trimethoprim / sulfamethoxazole (TMP / SMX) used as a therapy for ...

A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS

To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard tr...

Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

To compare the safety and effectiveness of an investigational drug therapy (trimetrexate plus leucovorin calcium) with that of conventional therapy (sulfamethoxazole-trimethoprim) in the t...

Trimethoprim-Sulfamethoxazole or Doxycycline for Skin and Soft Tissue Infections

Background: In many communities, skin and soft tissue infections (SSTI) with MRSA have become more prevalent than infections with β-lactam susceptible bacteria. This has necessitated alt...

PubMed Articles [126 Associated PubMed Articles listed on BioPortfolio]

Sulfamethoxazole/trimethoprim vs Fluoroquinolones for the Treatment of Stenotrophomonas maltophilia Bloodstream Infections.

Stenotrophomonas maltophilia causes high mortality rates, especially in bloodstream infections (BSI) where there is a lack of comparative data with fluoroquinolones (FQs) and sulfamethoxazole/trimetho...

Trimethoprim-sulfamethoxazole and antineutrophil cytoplasmic antibodies-associated vasculitis.

In antineutrophil cytoplasmic antibodies-associated vasculitis (AAV), the treatment of choice is either Rituximab or cyclophosphamide in combination with steroids. In less extended forms of AAV, howev...

Taking the Challenge: A Protocolized Approach to Optimize Pneumocystis Pneumonia Prophylaxis in Renal Transplant Recipients.

While trimethoprim-sulfamethoxazole is considered first-line therapy for Pneumocystis pneumonia prevention in renal transplant recipients, reported adverse drug reactions may limit use and increase re...

Risk factors for Pneumocystis jirovecii Pneumonia in Patients With Rheumatoid Arthritis and a Prophylactic Indication of Trimethoprim/Sulfamethoxazole.

Immunosuppressant medications (ISPs) increase the occurrence of Pneumocystis jirovecii pneumonia (PCP) in rheumatoid arthritis (RA) patients. The prophylactic administration of trimethoprim/sulfametho...

Advanced oxidation of real sulfamethoxazole + trimethoprim formulations using different anodes and electrolytes.

A commercial sulfamethoxazole + trimethoprim formulation has been degraded in 0.050 M Na2SO4 at pH 3.0 by electrochemical oxidation with electrogenerated H2O2 (EO-H2O2), electro-Fenton (EF), photoe...

Advertisement
Quick Search
Advertisement
Advertisement

 

Relevant Topics

Nutrition
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...

Pneumonia
Pneumonia (bronchopneumonia, lobar pneumonia and double pneumonia) is inflammation (swelling) of the tissue in one or both of your lungs. It is usually caused by an pneumococcal infection caused by bacteria called Streptococcus pneumoniae.  However,...


Drugs and Medication Quicklinks


Searches Linking to this Drug Record