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Minocycline Hydrochloride Capsules, USP | Minocycline Hydrochloride

12:47 EDT 24th July 2014 | BioPortfolio

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IMAGE minocycline-str.jpg

Reports from the laboratory providing results of the standard single-disk susceptibility test with a 30 mcg tetracycline or minocycline disk should be interpreted according to the following criteria:  

MIC (mcg/mL)
 Interpretation
≤4
 Susceptible (S)
8
 Intermediate (I)
≥16
 Resistant (R)
MIC (mcg/mL)
 Interpretation
≤2
 Susceptible (S)
4
 Intermediate (I)
≥8
 Resistant (R)
MIC (mcg/mL)
 Interpretation
≤0.25
 Susceptible (S)
0.5-1
 Intermediate (I)
≥2
 Resistant (R)
Microorganism
 MIC Range (mcg/mL)
 Escherichia coli ATCC 25922 0.5-2
 Enterococcus faecalis ATCC 29212 8-32
 Staphylococcus aureus ATCC 29213 0.25-1
 Haemophilus influenzae ATCC 49247 4-32
 Streptococcus pneumoniae ATCC 49619 0.12-0.5
 Neisseria gonorrhoeae ATCC 49226 0.25-1
Zone Diameter (mm)
 Interpretation
≥19
 Susceptible (S)
15-18
 Intermediate (I)
≤14
 Resistant (R)
Zone Diameter (mm)
 Interpretation
≥29
 Susceptible (S)
26-28
 Intermediate (I)
≤25
 Resistant (R)
Zone Diameter (mm)
 Interpretation
≥38
 Susceptible (S)
31-37
 Intermediate (I)
≤30
 Resistant (R)
Zone Diameter (mm)
 Interpretation
≥23
 Susceptible (S)
19-22
 Intermediate (I)
≤18
 Resistant (R)
Zone Diameter (mm)
 Interpretation
≥19
 Susceptible (S)
15-18
 Intermediate (I)
≤14
 Resistant (R)
Microorganism
Zone Diameter Range (mm)
Tetracycline
Minocycline
 Escherichia coli ATCC 25922 18-25
19-25
 Staphylococcus aureus ATCC 29213 24-30
25-30
 Haemophilus influenzae ATCC 49247 14-22
-
 Neisseria gonorrhoeae ATCC 49226 30-42
-
 Streptococcus pneumoniae ATCC 49619 27-31
-
IMAGE minocycline-fig1.jpgIMAGE minocycline-fig2.jpgIMAGE minocycline-fig3.jpg

Manufacturer

Aurobindo Pharma Limited

Active Ingredients

Source

Drugs and Medications [622 Associated Drugs and Medications listed on BioPortfolio]

Arestin [OraPharma, Inc.]

ARESTIN (minocycline hydrochloride) Microsperes, 1mg

Minocycline hydrochloride [Global Pharmaceuticals, Division of Impax Laboratories Inc.]

These highlights do not include all the information needed to use minocycline hydrochloride extended-release tablets safely and effectively. See full prescribing information for minocycline hydrochlor...

Minocycline hydrochloride [Sandoz Inc]

MINOCYCLINE HYDROCHORIDE EXTENDED RELEASE TABLETS (MINOCYCLINE HYDROCHORIDE, USP) These highlights do not include all the information needed to use minocycline hydrochloride extended-release tablets s...

Donepezil hydrochloride [Sun Pharmaceutical Industries Limited ]

These highlights do not include all the information needed to use donepezil hydrochloride safely and effectively. See full prescribing information for donepezil hydrochloride tablets Donepezil Hydroch...

Minocycline hydrochloride [Mylan Pharmaceuticals Inc.]

These highlights do not include all the information needed to use minocycline hydrochloride extended-release tablets safely and effectively. See full prescribing information for minocycline hydrochlor...

Clinical Trials [2187 Associated Clinical Trials listed on BioPortfolio]

Trial of Minocycline to Treat Children With Fragile X Syndrome

This is a single center study at the UC Davis MIND Institute in patients age 3.5-16 years of age with fragile X syndrome (FXS), funded by a National Fragile X Foundation Grant. It is a con...

Study 3: Minocycline Decreases Microglia Activation

This study is a mechanistic study that will enroll 9 subjects who are participating in NCT02133885 (which is designed to evaluate minocycline to test the hypothesis that minocycline treatm...

Safety and Efficacy Study of Copaxone Administered in Combination With Minocycline

This study investigates the add-on effect of oral minocycline in subjects treated with daily injection of Copaxone. Copaxone and minocycline are thought to have differential modes of actio...

Pilot Study of Minocycline in Huntington's Disease

This study is being conducted to assess the impact of minocycline on the progression of symptoms of HD. The study will also assess whether it is reasonable to continue with further study o...

Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults

The purpose of this study is to determine the effectiveness of minocycline, an antibiotic, in lessening the decreased mental function sometimes caused by anti-HIV drugs.

PubMed Articles [268 Associated PubMed Articles listed on BioPortfolio]

Minocycline susceptibility breakpoints for Acinetobacter baumannii: do we need to re-evaluate them?

Minocycline is an old broad-spectrum tetracycline indicated for the treatment of various infections, including those due to minocycline-susceptible Acinetobacter spp. Susceptibility data worldwide are...

Absence of TetB Identifies Minocycline-Susceptible Isolates of Acinetobacter baumannii.

Minocycline is one of the few options available to treat infections caused by Acinetobacter baumannii. Acquired resistance is associated with the presence of the TetB efflux pump. Previous studies sug...

Minocycline inhibits formalin-induced inflammatory pain and the underlying mechanism.

To unravel the underlying mechanism of minocycline in formalin-induced inflammatory pain, and to investigate the effects of minocycline on synaptic transmission in substantia gela-tinosa (SG) neurons ...

Minocycline decreases Th2 chemokines from M2 macrophages: possible mechanisms for the suppression of bullous pemphigoid by traditional bullous disease drugs.

Minocycline/tetracycline is clinically used for the treatment of bullous pemphigoid (BP), and its clinical benefits are superior to those of prednisolone when considering adverse events. Although the ...

The role of minocycline in alleviating aluminum phosphide-induced cardiac hemodynamic and renal toxicity.

Poisoning with aluminum phosphide (AlP) has been attributed to the high rate of mortality among many Asian countries. It affects several organs, mainly heart and kidney. Numerous literature demonstrat...

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