NA | Phentermine Hydrochloride [H.J. Harkins Company, Inc.] | BioPortfolio

13:17 EST 27th January 2019 | BioPortfolio

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Phentermine hydrochloride tablets USP are indicated as a short-term (a few weeks) adjunct in a regimen

of weight reduction based on exercise, behavioral modification and caloric restriction in the

management of exogenous obesity for patients with an initial body mass index greater than or equal to

30 kg/m , or greater than or equal to 27 kg/m in the presence of other risk factors (e.g., controlled

hypertension, diabetes, hyperlipidemia). Below is a chart of body mass index (BMI) based on various heights and weights.

BMI is calculated by taking the patient's weight, in kilograms (kg), divided by the patient's height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches x 0.0254 = meters.

Phentermine hydrochloride USP is a sympathomimetic amine anorectic. Its chemical name is a,a- dimethylphenethylamine hydrochloride. The structural formula is as follows:

Phentermine hydrochloride USP is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether.

Phentermine hydrochloride tablets USP are available as an oral tablet containing 37.5 mg of phentermine hydrochloride USP (equivalent to 30 mg of phentermine base). Each phentermine hydrochloride tablet USP also contains the inactive ingredients microcrystalline cellulose, pregelatinized starch, anhydrous lactose, crospovidone, colloidal silicon dioxide, magnesium stearate, sucrose, corn starch and FD&C Blue #1.


H.J. Harkins Company, Inc.

Active Ingredients


Drugs and Medications [345 Associated Drugs and Medications listed on BioPortfolio]

Phentermine hydrochloride [northwind pharmaceuticals]


Phentermine hcl [direct rx]


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Phentermine hydrochloride [blenheim pharmacal, inc.]


Phentermine hydrochloride [physicians total care, inc.]


Clinical Trials [2212 Associated Clinical Trials listed on BioPortfolio]

Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants

The purpose of this study is to compare the effects of canagliflozin and phentermine to those of placebo to promote on a change in body weight over a 26 week period.

Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults

The primary objective of this study is to describe the single- and multiple-dose pharmacokinetic profiles of two novel formulations of topiramate and commercially available immediate relea...

A Study to Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment

VI-0521, a fixed dose combination of immediate-release (IR) phentermine and controlled-release (CR) topiramate, is in Phase III clinical development as a potential therapy for obesity. In ...

Phentermine/Gastric Band Weight Loss Study

This is a prospective, randomized, double-blind controlled trial. The goal is to show whether the administration of daily oral Phentermine will augment patient weight loss and resolve obe...

Individualized Obesity Pharmacotherapy

The researchers are trying to identify the specific characteristics (phenotypes) that may be useful to help select the right medication for weight loss.

PubMed Articles [212 Associated PubMed Articles listed on BioPortfolio]

Recurrent Psychosis after Phentermine Administration in a Young Female: A Case Report.

Phentermine is a sympathomimetic amine, like amphetamine, which is one of the most often prescribed drugs for weight loss. Although exact mechanism of phentermine causing psychosis is still not clear,...

Phentermine: A Systematic Review for Plastic and Reconstructive Surgeons.

Phentermine is the most prescribed antiobesity drug in America, with 2.43 million prescriptions written in 2011. Case reports suggest there are anesthetic risks, such as refractory hypotension, involv...

Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats.

Berberine hydrochloride is one the effective compound among Rhizoma Coptidis, Cortex Phellodendri, and other plants. There are several clinical functions of berberine hydrochloride including anti-infl...

In vitro and in vivo performance of epinastine hydrochloride-releasing contact lenses.

A number of drug-releasing contact lenses are currently being studied to address issues inherent in eye drops as a drug delivery method. In this study, we developed epinastine hydrochloride-releasing ...

Phentermine associated recurrent intracerebral hemorrhage.

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