NA | Salicylic Acid [Rochester Pharmaceuticals] | BioPortfolio

13:23 EST 27th January 2019 | BioPortfolio

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Salicylic Acid, 26%


Salicylic Acid, 26% is a topical preparation for treatment of common and plantar warts, in a film-forming vehicle composed of acrylates copolymer, isopropyl alcohol, isobutyrate, n-butyl acetate, and polyvinyl butyral.  The pharmacologic activity of this medication is generally attributed to the keratolytic activity of salicylic acid which is incorporated into a film-forming vehicle designed to cover the wart without the need for a bandage. The chemical structural formula of salicylic acid is:

Although the exact mode of action of salicylic acid in the treatment of warts is not known, its activity appears to be associated with its keratolytic action which results in mechanical removal of epidermal cells infected with wart viruses.

Salicylic Acid, 26% is indicated for the topical treatment and removal of common warts and plantar warts.

Salicylic Acid, 26% should not be used by diabetics or patients with impaired blood circulation. Salicylic Acid, 26% should not be used on moles, birthmarks, unusual warts with hair growing from them or warts on the face.

Salicylic Acid, 26% is for external use only. Do not permit Salicylic Acid, 26% to contact eyes or mucous membranes.  If contact with eyes or mucous membranes occurs, immediately flush with water for 15 minutes. Salicylic Acid, 26% should not be allowed to contact normal skin surrounding the wart. Treatment should be discontinued if excessive irritation occurs. Salicylic Acid, 26% is flammable and should be kept away from fire or flame. Keep bottle tightly capped when not in use.

A localized irritant reaction may occur if Salicylic Acid, 26% is applied to the normal skin surrounding the wart.  Any irritation may normally be controlled by temporarily discontinuing use and by applying the medication only to the wart site when treatment is resumed.

Prior to application of Salicylic Acid, 26%, soak wart in warm water for five minutes.  Remove any loosened tissue by gently rubbing with a brush, wash cloth or emery board. Dry thoroughly. Using the brush applicator supplied, apply twice to entire wart surface, allowing the first application to dry before applying the second. Treatment should be once or twice a day and should continue as directed by physician. Be careful not to apply to surrounding skin.  Clinically visible improvement will normally occur during the first or second week of therapy.  Maximum resolution may be expected after four to six weeks of drug use.

Salicylic Acid, 26% is supplied in 10 mL amber bottles with a brush applicator - NDC 49908-137-10

Store at 20ºC to 25ºC (68ºF to 77ºF), excursions permitted between 15ºC and 30ºC (between 59ºF and 86ºF). Brief exposure to temperatures up to 40ºC (104ºF) may be tolerated provided the mean kinetic temperature does not exceed 25ºC (77ºF); however, such exposure should be minimized. Protect from freezing.


Manufactured for: Rochester Pharmaceuticals Doylestown, PA 18901 1-866-458-1772


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Rochester Pharmaceuticals

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Clinical Trials [2825 Associated Clinical Trials listed on BioPortfolio]

Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women

This study will enroll 20 adult Hispanic women. Participants will apply 4% hydroquinone cream twice daily to affected areas on the face for 14 weeks and half the face will be peeled with ...

Use of Acetyl Salicylic Acid and Terbutalin in Assisted Reproductive Techniques (ART)

This study aims to determine the possible effects of Acetyl Salicylic Acid (ASA) and Terbutalin on ART treatment.

Comparing the Efficacy and Safety of Combined Glycolic Acid and Salicylic Acid Peel Versus Glycolic Acid Peel Alone in the Treatment of Melasma: A Split Face Study

Melasma is an acquired form of hyperpigmentation that is seen most commonly on the face, characterized by symmetrically distributed brown patches of variable darkness. The cosmetically una...

Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammatory Agent in Acne Vulgaris

The concept behind our study was to combine an effect of antibiotic and anti-inflammatory agents for a more efficient acne therapy directed at the factors involved in the pathophysiology o...

Anti-programmed Cell Death-1 Ligand 1 (PDL-1) Antibody Atezolizumab, Bevacizumab and Acetyl Salicylic Acid in Recurrent Platinum Resistant Ovarian Cancer

This is a randomized phase II study, aimed at evaluating the efficacy (through progression free survival at 6 months) and safety of 5 different treatments involving atezolizumab, bevacizum...

PubMed Articles [6479 Associated PubMed Articles listed on BioPortfolio]

Determination of Salicylic Acid in Feed Using LC-MS/MS.

Salicylic acid is a derivative of benzoic acid and occurs in nature. The main target of this study was to develop the liquid chromatography coupled with tandem mass spectrometry technique as a method ...

New salicylic acid and pyroglutamic acid conjugated derivatives confer protection to bread wheat against Zymoseptoria tritici.

To promote sustainable agriculture and healthy food, research that contributes towards a new generation of eco-friendly phytosanitary compounds are increasingly encouraged. The plant hormone salicylic...

Metabolic Alternations of Amino Acids, γ-Aminobutyric Acid, and Salicylic Acid in Solanum lycopersicum (L.) Following Preplanting Seedling Spray with Salicylic Acid.

Preplanting foliar spray of salicylic acid (SA) (0.0, 5.0, and 10.0 μg/mL) to Solanum lycopersicum (L.) altered the metabolite profile of amino acids, γ-aminobutyric acid (GABA), and SA in leaf, roo...

A novel treatment for idiopathic knuckle pads with cantharidin-podophylotoxin-salicylic acid.

Knuckle pads are benign subcutaneous nodules that appear most frequently on the small joints of the hands. In children, they are often idiopathic, and no universally effective treatment has been repor...

A pendant peptide endows a sunscreen with water-resistance.

Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain sal...

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