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LORAZEPAM .5mg | LORAZEPAM [DIRECTRX] | BioPortfolio

13:35 EST 27th January 2019 | BioPortfolio

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Lorazepam, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one: Lorazepam structure

It is a nearly white powder almost insoluble in water. Each Lorazepam Tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of lorazepam. The inactive ingredients present are Lactose Anhydrous, Microcrystalline Cellulose, Polacrilin Potassium and Magnesium Stearate.

Lorazepam is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.

The effectiveness of Lorazepam in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.

Manufacturer

DIRECTRX

Active Ingredients

Source

Clinical Trials [54 Associated Clinical Trials listed on BioPortfolio]

Lorazepam-Induced Toxicity in the Aged

This study will compare the effects of an acute dose of lorazepam to a placebo in elderly patients with generalized anxiety disorder (GAD).

A Sedation/Cognition/Electroencephalogram (EEG) Study Using AZD7325 and Comparator.

The purpose of the study is to determine the effects of the compound AZD7325 as compared to lorazepam on sleepiness, concentration and brain activity.

Exploring the Effects of Diazepam and Lorazepam

Aims : - exploring lorazepam (0.038 mg/kg) effects, after a single oral intake, in healthy volunteers, on the neural correlates of encoding and retrieval of information during a ...

Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department Care

In this proposal, the investigators will determine if a single dose of oral lorazepam reduces distress, pain severity, and need for opiate analgesics both in the ED and in the acute recove...

Fasting Study of Lorazepam Tablets 2 mg and Ativan Tablets 2 mg

The objective of this study was to investigate the bioequivalence of Mylan's lorazepam 2 mg tablets to Wyeth's Ativan 2 mg tablets following a single, oral 2 mg (1 x 2 mg) dose administere...

PubMed Articles [7 Associated PubMed Articles listed on BioPortfolio]

Effects of lorazepam and baclofen on short- and long-latency afferent inhibition.

Short-latency afferent inhibition (SAI) is modulated by GABA receptor activity while the pharmacological origin of long-latency afferent inhibition remains unknown. This is the first study to report t...

Sleeping beauty syndrome presenting with insomnia.

A young man previously diagnosed with Kleine-Levin syndrome (KLS) presented with abnormal behaviour over the last 8 days. This included decreased sleeping hours and appetite, hypersexuality, aggressiv...

Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus.

Diazepam is labeled for status epilepticus (SE) in children, but there are limited data characterizing its disposition in pediatric patients. We developed a population pharmacokinetic (PK) model of i....

Geriatrics Literature 2017 Year in Review.

We present 11 of the most effective articles from 2017 in geriatric medicine. Studies address topics including self-driven advance care planning, unnecessary emergency department transfers from assist...

Psychoactive pharmaceuticals and illicit drugs in coastal waters of North-Western Spain: Environmental exposure and risk assessment.

The knowledge on the presence of pharmaceutical compounds, and possible risks, in coastal and marine systems is still limited. This study represents the first attempt at monitoring psychoactive pharma...

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