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Salicylic Acid, 27.5% | Salicylic Acid [Trinity Pharmaceuticals, LLC] | BioPortfolio

13:35 EST 27th January 2019 | BioPortfolio

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Rx only

FOR DERMATOLOGICAL USE ONLY. NOT FOR OPHTHALMIC, ORAL OR INTRAVAGINAL USE.

Salicylic Acid, 27.5% is a topical preparation containing 27.5% Salicylic Acid in a film-forming vehicle composed of: acrylates copolymer, isopropyl alcohol, isobutyrate, n-butyl acetate, and polyvinyl butyrate. The pharmacologic activity of this medication is generally attributed to the keratolytic activity of salicylic acid which is incorporated into a film-forming vehicle designed to cover the wart without the need for a bandage. The chemical structural formula of salicylic acid is:

Although the exact mode of action for salicylic acid in the treatment of warts is unknown, its activity appears to be associated with its keratolytic action, which results in mechanical removal of epidermal cells infected with wart viruses.

Salicylic Acid, 27.5% is indicated for the topical treatment and removal of common warts and plantar warts.

Salicylic Acid, 27.5% should not be used by diabetics or patients with impaired blood circulation. Salicylic Acid, 27.5% should not be used on moles, birthmarks, unusual warts with hair growing from them or warts on the face.

Salicylic Acid, 27.5% is for external use only. Do not permit Salicylic Acid, 27.5% to contact eyes or mucous membranes. If contact with eyes or mucous membranes occurs, immediately flush with water for 15 minutes. Salicylic Acid, 27.5% should not be allowed to contact normal skin surrounding the wart. Treatment should be discontinued if excessive irritation occurs. Salicylic Acid, 27.5% is flammable and should be kept away from fire or flame.  Keep bottle tightly capped when not in use.

A localized irritant reaction may occur if Salicylic Acid, 27.5% is applied to the normal skin surrounding the wart. Any irritation may normally be controlled by temporarily discontinuing use and by applying the medication only to the wart site when treatment is resumed.

Prior to application of Salicylic Acid, 27.5% soak wart in warm water for five minutes. Remove any loosened tissue by gently rubbing with a brush, wash cloth, emery board or pumice stone. Dry thoroughly. Using the brush applicator supplied, apply twice to entire wart surface, allowing the first application to dry before applying the second. Treatment should be once or twice a day and should continue as directed by physician. Be careful not to apply to surrounding skin.  Clinically visible improvement will normally occur during the first or second week of therapy. Maximum resolution may be expected after four to six weeks of drug use.

Salicylic Acid, 27.5% is supplied in 10 mL amber glass bottles with brush applicator - NDC 54295-304-11.

Store at 20ºC to 25ºC (68ºF to 77ºF)., excursions permitted between 15ºC and 30ºC (between 59ºF and 86ºF). Brief exposure to temperatures up to 40ºC (104ºF) may be tolerated provided the mean kinetic temperature does not exceed 25ºC (77ºF); however, such exposure should be minimized. Protect from freezing.

KEEP THIS AND ALL MEDICATIONS OUT OF REACH OF CHILDREN.

Marketed By: Trinity Pharmaceuticals LLC 1 International Plaza, Suite 550 Philadelphia, PA 19113 TrinityPharmaLLC.com REV 11/13

NDC 54295-304-11

Rx only

For topical use onlyNot for ophthalmic use

Salicylic Acid, 27.5%10 mL

Manufacturer

Trinity Pharmaceuticals, LLC

Active Ingredients

Source

Clinical Trials [2825 Associated Clinical Trials listed on BioPortfolio]

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PubMed Articles [6479 Associated PubMed Articles listed on BioPortfolio]

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Salicylic acid is a derivative of benzoic acid and occurs in nature. The main target of this study was to develop the liquid chromatography coupled with tandem mass spectrometry technique as a method ...

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Metabolic Alternations of Amino Acids, γ-Aminobutyric Acid, and Salicylic Acid in Solanum lycopersicum (L.) Following Preplanting Seedling Spray with Salicylic Acid.

Preplanting foliar spray of salicylic acid (SA) (0.0, 5.0, and 10.0 μg/mL) to Solanum lycopersicum (L.) altered the metabolite profile of amino acids, γ-aminobutyric acid (GABA), and SA in leaf, roo...

A novel treatment for idiopathic knuckle pads with cantharidin-podophylotoxin-salicylic acid.

Knuckle pads are benign subcutaneous nodules that appear most frequently on the small joints of the hands. In children, they are often idiopathic, and no universally effective treatment has been repor...

A pendant peptide endows a sunscreen with water-resistance.

Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain sal...

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