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NA | Sulfamethoxazole and Trimethoprim [Aurobindo Pharma Limited] | BioPortfolio

13:45 EST 27th January 2019 | BioPortfolio

Note: While we endeavour to keep our records up-to-date one should not rely on these details being accurate without first consulting a professional. Click here to read our full medical disclaimer.

To reduce the development of drug-resistant bacteria and maintain the effectiveness of sulfamethoxazole and trimethoprim tablets and other antibacterial drugs, sulfamethoxazole and trimethoprim tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

 

Weight
Dose–every 12 hours
lb
kg
Tablets
22
44
66
88
10
20
30
40

1

2 or 1 DS tablet
Creatinine Clearance (mL/min)
Recommended Dosage Regimen
Above 30
15–30
Below 15
Usual standard regimen
½ the usual regimen
Use not recommended
Weight
Dose–every 6 hours
lb
kg
Tablets
18
35
53
70
88
106
141
176
8
16
24
32
40
48
64
80

1

2 or 1 DS tablet

3 or 1½  DS tablets
4 or 2 DS tablets
5 or 2½ DS tablets
Body Surface Area
Dose–every 12 hours
(m2)
Tablets
0.26
0.53
1.06

½
1

Manufactured for: Aurobindo Pharma USA, Inc. 2400 Route 130 NorthDayton, NJ 08810 Manufactured by: Aurobindo Pharma Limited Unit-VII (SEZ)Mahaboob Nagar (Dt)AP-509302, INDIA Revised: 09/2012

3000 Tablets Batch      : Mfg         : Expiry      : To be repacked within six months from the date of manufacturing NDC 65862-419-39 BULK SHIPMENTPLEASE HANDLE CAREFULLY Rx only Sulfamethoxazole and Trimethoprim Tablets, USP 400 mg/80 mg Each tablet contains: Sulfamethoxazole USP .........................................400 mgTrimethoprim USP ....................................................80 mg CAUTION: FOR REPACKAGING ONLY Store at 20° to 25°C (68° to 77°F); excursions permitted to 15°to 30°C (59° to 86°F) [see USP Controlled Room Temperature]. Manufactured by: Aurobindo Pharma Limited Unit-VII (SEZ)Mahaboob Nagar (Dt)AP-509302, INDIA M.L.No.: 22/MN/AP/2009/F/G

Manufacturer

Aurobindo Pharma Limited

Active Ingredients

Source

Clinical Trials [82 Associated Clinical Trials listed on BioPortfolio]

Prophylactic Trimethoprim/Sulfamethoxazole to Prevent Severe Infections in Patients With Lupus Erythematous

The purpose of this study is to determine whether trimethoprim/sulfamethoxazole is effective in preventing serious infectious complications (those that require hospitalization or lead to d...

A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome

The primary objective of the study is to evaluate the effectiveness of l-leucovorin in preventing toxicity from high dose trimethoprim / sulfamethoxazole (TMP / SMX) used as a therapy for ...

A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS

To evaluate the effectiveness of two oral treatments for mild to moderate Pneumocystis carinii pneumonia (PCP): dapsone/trimethoprim or clindamycin/primaquine as compared to a standard tr...

Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

To compare the safety and effectiveness of an investigational drug therapy (trimetrexate plus leucovorin calcium) with that of conventional therapy (sulfamethoxazole-trimethoprim) in the t...

Trimethoprim-Sulfamethoxazole or Doxycycline for Skin and Soft Tissue Infections

Background: In many communities, skin and soft tissue infections (SSTI) with MRSA have become more prevalent than infections with β-lactam susceptible bacteria. This has necessitated alt...

PubMed Articles [146 Associated PubMed Articles listed on BioPortfolio]

In Vitro Bactericidal Activity of Trimethoprim-Sulfamethoxazole/Colistin Combination Against Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates.

Carbapenem-resistant Klebsiella pneumoniae (CRKP) has emerged as a formidable health challenge in recent years owing to the shortage of effective antibiotics. Colistin is the last and sometimes the on...

Trimethoprim-sulfamethoxazole vs. colistin or ampicillin-sulbactam for the treatment of carbapenem-resistant Acinetobacter baumannii: a retrospective matched cohort study.

We aimed to assess the effectiveness of trimethoprim-sulfamethoxazole (TMP/SMX) as monotherapy for the treatment of carbapenem-resistant A. baumannii (CRAB) infections.

Physiologically Based Pharmacokinetic Modeling for Trimethoprim and Sulfamethoxazole in Children.

The aims of this study were to (1) determine whether opportunistically collected data can be used to develop physiologically based pharmacokinetic (PBPK) models in pediatric patients; and (2) characte...

Impact of Trimethoprim-Sulfamethoxazole Urinary Tract Infection Prophylaxis on Non-UTI Infections.

In this secondary analysis of the Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) cohort, we found that daily prophylaxis with trimethoprim-sulfamethoxazole was not associated ...

Fluoroquinolones versus trimethoprim-sulfamethoxazole for the treatment of Stenotrophomonas maltophilia infections: A systematic review and meta-analysis.

Fluoroquinolones (FQs) are a popular alternative to trimethoprim-sulfamethoxazole (STX) for Stenotrophomonas maltophilia infections.

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