Biotechnology, Medical and Healthcare Research Resources

20:47 EDT 21st July 2018 | BioPortfolio

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Global Clinical Trials Database

We have an extensive database of clinical trials which is updated daily. View our full Clinical Trials Database

A Study Evaluating the Safety of Cal-1 (LVsh5/C46) Drug Product in HIV-1 Infected Patient With High Risk Lymphoma

The purpose of this study is to evaluate the safety and the feasibility, and the success of engraftment of the introduction of Cal-1 gene-transduced haematopoietic cell populations (Ttn and HSPCtn) in patients with HIV-1-related high-risk lymphoma.

11:55 EDT 21 Jul 2018

A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered APL-2 in Subjects With PNH

This is a Phase IIa, open-label, multiple dose, study in patients with PNH who have not received eculizumab (Soliris ®) in the past. A single cohort of subjects is planned for evaluation.

11:55 EDT 21 Jul 2018

Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia

1. To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia 2. To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a t...

11:55 EDT 21 Jul 2018

Study to Evaluate Safety & Tolerability of AGI-134 in Solid Tumour

This study will evaluate if AGI-134 given alone and in combination with pembrolizumab is safe and effective in treating patients with unresectable metastatic solid tumours.

11:55 EDT 21 Jul 2018

Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers

A Ten Sequence, Open Label, Randomized Crossover Study Comparing Nicotine Pharmacokinetics of JUUL 1.7% and JUUL 5% Nicotine Salt Based ENDS Products, in Healthy Adult Smokers.

11:55 EDT 21 Jul 2018

PubMed Journal Articles

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Early and mid-term outcomes after surgical repair of congenital supravalvular aortic stenosis with the Doty technique.

The aim of this study was to evaluate the efficacy and safety of the Doty surgical approach in pediatric patients with congenital supravalvular aortic stenosis (SVAS) by examining early and mid-term outcomes.

08:00 EDT 1 Jul 2018

Multivessel coronary-cameral fistulas associated with ventricular fibrillation: an unusual case.

Coronary-cameral fistula (CCF) is a rare connection between a coronary artery and a chamber of the heart. It most often derives from the right coronary artery and drains into the right ventricle. CCF originating from all 3 major coronary vessels and draining into the left heart is an extremely rare coronary artery malformation. A 47-yearold-man who was admitted to the clinic with angina pectoris a...

08:00 EDT 1 Jul 2018

Transient ST-segment elevation due to coronary slow flow during cryoballoon application.

This report is a description of a rare case of transient ST-segment elevation during cryoballoon application for paroxysmal atrial fibrillation (PAF). A 74-year-old male with symptomatic PAF was referred to the center for ablation. During cryoablation of the left superior pulmonary vein (188 seconds, -48°C), ST-segment elevation in the anterolateral leads was observed suddenly, though without any...

08:00 EDT 1 Jul 2018

Acute myocardial infarction associated with clomiphene citrate in a young woman.

Clomiphene citrate is a drug that stimulates ovulation and is commonly used in cases of female infertility. Generally, it is recognized as a safe agent for ovulation induction, but rarely, it is associated with life-threatening conditions. A 36-year-old woman who had been prescribed clomiphene citrate for infertility was admitted to the emergency department for chest pain lasting for 2 hours. She ...

08:00 EDT 1 Jul 2018

Successful cryoablation of incessant fast-slow atypical atrioventricular nodal reentrant tachycardia in a child with tachycardia-induced cardiomyopathy.

A 15-year-old female patient presented at the clinic with heart failure (HF). A 12-lead electrocardiogram showed a heart rate of 170 bpm; negative P waves in leads DII, DIII, aVF; and long RP tachycardia (LRPT). Echocardiography demonstrated a shortening fraction (SF) of 20%. An electrophysiology study during tachycardia revealed an atrial-His time of 52 milliseconds and a His-atrial interval of 2...

08:00 EDT 1 Jul 2018

Drugs and Medication Records

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