Advertisement

Topics

Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension.

08:00 EDT 16th October 2015 | BioPortfolio

Summary of "Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension."

The minor alleles of 3 FOXO3 single nucleotide polymorphisms (SNPs)-rs2802292, rs2253310, and rs2802288-are associated with human longevity. The aim of the present study was to test these SNPs for association with blood pressure (BP) and essential hypertension (EHT).

Affiliation

Journal Details

This article was published in the following journal.

Name: American journal of hypertension
ISSN: 1941-7225
Pages:

Links

DeepDyve research library

PubMed Articles [32431 Associated PubMed Articles listed on BioPortfolio]

Longevity-Associated Forkhead Box O3 (FOXO3) Single Nucleotide Polymorphisms are Associated with Type 2 Diabetes Mellitus in Chinese Elderly Women.

BACKGROUND This study aimed to investigate the association of single nucleotide polymorphisms (SNPs) of Forkhead box O3 (FOXO3) gene with type 2 diabetes mellitus (T2D). MATERIAL AND METHODS A total o...

Association of Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study.

[] encodes dimethylaniline monooxygenase [N-oxide-forming] 3, which breaks down nitrogen-containing compounds, and has been implicated in blood pressure regulation. Studies have reported conflicting r...

Analysis of FOXO3 Gene Polymorphisms Associated with Human Longevity.

Next-generation DNA sequencing has ushered in a new era of genotype-phenotype comparisons that have the potential to elucidate the genetic nature of complex traits. Since such methods rely on short se...

FOXO3, a Molecular Search for the Fountain of Youth.

FOXO3 has been consistently associated with longevity and with a reduction in the prevalence of cardiovascular disease. In this issue, Yan et al. (2019) report that FOXO3-activated vascular cells der...

Leptin mediates the relationship between fat mass and blood pressure: The Hamamatsu School-based health study.

Animal studies have shown that leptin mediates the association between obesity and hypertension. However, only a few studies have assessed this relationship in population-based epidemiological studies...

Clinical Trials [12998 Associated Clinical Trials listed on BioPortfolio]

C-Reactive Protein (CRP) Gene Variants and Coronary Artery Disease in a Chinese Han Population

The recognition of the association between circulating C-reactive protein (CRP) levels and risk of coronary heart disease (CHD) has led to an increased emphasis on CRP genetic effects on C...

Association of Genetic Polymorphisms With Atrial Fibrosis and Thrombogenic Substrate in Patients With Non-valvular Atrial Fibrillation

Atrial fibrillation (AF) is the most frequently encountered cardiac arrhythmia. Emerging data suggests that common genetic variants are associated with the development of AF. The main feat...

A Study to Explore the Association Between Blood Pressure, HIV and Antiretroviral Therapy

The purpose of this study is to explore the association between blood pressure, HIV and/or its treatment in a cross sectional observational study.

Effectiveness of Vitamin D Supplementation

This pilot study will examine the effectiveness of vitamin D supplementation on reducing blood pressure and improving endothelial function. Premenopausal African American women will be re...

The Association Between Central Aortic Blood Pressure Indices and Severity of Coronary Artery Disease

Abstract Objectives: Primary: To study the association between central aortic blood pressure indices and coronary artery disease in patients undergoing elective angiography. Second...

Medical and Biotech [MESH] Definitions

Method in which repeated blood pressure readings are made while the patient undergoes normal daily activities. It allows quantitative analysis of the high blood pressure load over time, can help distinguish between types of HYPERTENSION, and can assess the effectiveness of antihypertensive therapy.

Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.

PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.

The blood pressure in the VEINS. It is usually measured to assess the filling PRESSURE to the HEART VENTRICLE.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Searches Linking to this Article