Differential serotonergic innervation of the amygdala in bonobos and chimpanzees.

08:00 EDT 16th October 2015 | BioPortfolio

Summary of "Differential serotonergic innervation of the amygdala in bonobos and chimpanzees."

Humans' closest living relatives are bonobos (Pan paniscus) and chimpanzees (Pan troglodytes), yet these great ape species differ considerably from each other in terms of social behavior. While bonobos are more tolerant of conspecifics in competitive contexts and often use sexual behavior to mediate social interactions, chimpanzees more frequently employ aggression during conflicts and actively patrol territories between communities. Regulation of emotional responses is facilitated by the amygdala, which also modulates social decision-making, memory, and attention. Amygdala responsiveness is further regulated by the neurotransmitter serotonin. We hypothesized that the amygdala of bonobos and chimpanzees would differ in its neuroanatomical organization and serotonergic innervation. We measured volumes of regions and the length density of serotonin transporter-containing axons in the whole amygdala and its lateral, basal, accessory basal, and central nuclei. Results showed that accessory basal nucleus volume was larger in chimpanzees than bonobos. Of particular note, the amygdala of bonobos had more than twice the density of serotonergic axons than chimpanzees, with the most pronounced differences in the basal and central nuclei. These findings suggest that variation in serotonergic innervation of the amygdala may contribute to mediating the remarkable differences in social behavior exhibited by bonobos and chimpanzees.


Journal Details

This article was published in the following journal.

Name: Social cognitive and affective neuroscience
ISSN: 1749-5024


DeepDyve research library

PubMed Articles [3144 Associated PubMed Articles listed on BioPortfolio]

Higher fundamental frequency in bonobos is explained by larynx morphology.

Acoustic signals, shaped by natural and sexual selection, reveal ecological and social selection pressures [1]. Examining acoustic signals together with morphology can be particularly revealing. But t...

New Observations of Meat Eating and Sharing in Wild Bonobos (Pan paniscus) at Iyema, Lomako Forest Reserve, Democratic Republic of the Congo.

Bonobos (Pan paniscus) consume a variety of vertebrates, although direct observations remain relatively rare compared to chimpanzees (Pan troglodytes). We report the first direct observations of meat ...

Amygdala reactivity as a marker of differential susceptibility to socioeconomic resources during early adulthood.

Models of differential susceptibility hypothesize that neural function may be a marker of differential susceptibility to context, but no studies have tested this hypothesis. Using a sample of 310 youn...

Aggression by male bonobos against immature individuals does not fit with predictions of infanticide.

The selective advantage of male infanticide is enhancement of reproductive success of the aggressor. This implies that aggression is directed at individuals sired by others, infant loss shortens the m...

Intrahippocampal administration of 5-HT receptor drugs on memory consolidation and amnesia protocols.

To our knowledge the intrahippocampal serotonergic 5-HT receptor tone on memory and amnesia models remains unexplored. Hence, in the present work we tested intrahippocampal administration of serotonin...

Clinical Trials [544 Associated Clinical Trials listed on BioPortfolio]

Prevention of Graft Bone Resorption in Mandible Reconstruction by Innervation

The purpose of this study is to determine the efficacy of simultaneous innervation to prevent graft bone resorption in maxillofacial reconstruction. It may provide basis for future clinica...

Sympathetic Innervation of the Heart and Cardiac Resynchronization Therapy(CRT)

The purpose of this study is to assess whether baseline sympathetic innervation in patients with chronic heart failure (CHF) is predictive for response to cardiac resynchronization therapy...

Neurofeedback of Amygdala Activity for Post-traumatic Stress Disorder

The primary purpose of this study is to investigate the efficacy of neurofeedback (NF) of real-time functional magnetic resonance imaging (rt-fMRI) data of the amygdala with regards to the...

Antidepressant Discontinuation in Treatment Resistant Depression

The purpose of this study is to compare the effects on depressive symptoms of subjects who discontinue serotonergic antidepressants (a certain type of antidepressant, such as Prozac, that ...

Effects of Amygdala Neurofeedback on Depressive Symptoms

The purpose of this study is to determine the clinical efficacy of augmenting cognitive-behavioral therapy with real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) tr...

Medical and Biotech [MESH] Definitions

Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe. The amygdala is part of the limbic system.

Raphe nuclei located in the midbrain including the dorsal and median raphe nuclei. They are the origin of the major serotonergic innervation in the FOREBRAIN.

Differential thermal analysis in which the sample compartment of the apparatus is a differential calorimeter, allowing an exact measure of the heat of transition independent of the specific heat, thermal conductivity, and other variables of the sample.

Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.

A strain of PRIMATE T-LYMPHOTROPIC VIRUS 2 isolated from Congolese bonobos (PAN PANISCUS).

Quick Search


DeepDyve research library

Relevant Topics

Sexual Health
The World Health Organization (WHO) definition of sexual health; "the state of physical, emotional, mental and social well-being related to sexuality; it is not merely the absence of disease, dysfunction and infirmity. Sexual health requires a posit...

Selective serotonin reuptake inhibitors SSRIs
Serotonin and norepinephrine reuptake inhibitors (SNRIs) are a class of medications that are effective at easing depression symptoms. SNRIs are also sometimes used to treat other conditions such as anxiety and nerve pain. How SNRIs work Serotonin (se...

Searches Linking to this Article