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THE ASSOCIATION OF INDIVIDUAL AND REGIONAL SOCIOECONOMIC STATUS ON INITIAL PERITONITIS AND OUTCOMES IN PERITONEAL DIALYSIS PATIENTS: A PROPENSITY SCORE-MATCHED COHORT STUDY.

08:00 EDT 16th October 2015 | BioPortfolio

Summary of "THE ASSOCIATION OF INDIVIDUAL AND REGIONAL SOCIOECONOMIC STATUS ON INITIAL PERITONITIS AND OUTCOMES IN PERITONEAL DIALYSIS PATIENTS: A PROPENSITY SCORE-MATCHED COHORT STUDY."

♦ Background: Research indicates that the socioeconomic status (SES) of individuals and the area where they live are related to initial peritonitis and outcomes in peritoneal dialysis (PD). We conducted a retrospective, multi-center cohort study in China to examine these associations. ♦ Methods: Data on 2,171 PD patients were collected from 7 centers, including baseline demographic, socioeconomic, and laboratory data. We explored the potential risk factors for initial peritonitis and outcomes using univariate Cox regression and unadjusted binary logistic regression. Then, we used propensity score matching to balance statistically significant risk factors for initial peritonitis and outcomes, and Kaplan-Meier survival analysis to compare differences in peritonitis-free rates between different groups of participants after matching. ♦ Results: A total of 563 (25.9%) initial episodes of peritonitis occurred during the study period. The Kaplan-Meier peritonitis-free rate curve showed high-income patients had a significantly lower risk than low-income patients (p = 0.007) after matching for age, hemoglobin, albumin, and regional SES and PD center. The risk of treatment failure was significantly lower in the high-income than the low-income group after matching for the organism causing peritonitis and PD center: odds ratio (OR) = 0.27 (0.09 - 0.80, p = 0.018). Regional SES and education were not associated with initial peritonitis and outcomes. ♦ Conclusions: Our study demonstrates low individual income is a risk factor for the initial onset of peritonitis and treatment failure after initial peritonitis.

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This article was published in the following journal.

Name: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis
ISSN: 1718-4304
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INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.

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