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Gut-Busters: IL-17 Ain't Afraid of No IL-23.

08:00 EDT 20th October 2015 | BioPortfolio

Summary of "Gut-Busters: IL-17 Ain't Afraid of No IL-23."

Interleukin-23 (IL-23) is considered a critical regulator of IL-17 in lymphocytes. Whereas antibodies targeting IL-23 ameliorate colitis, IL-17 neutralization exacerbates disease. In this issue, Cua and colleagues and Maxwell and colleagues show that IL-17 maintains intestinal barrier integrity, helping explain this dichotomy (Lee et al., 2015; Maxwell et al., 2015).

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This article was published in the following journal.

Name: Immunity
ISSN: 1097-4180
Pages: 620-622

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