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Discovering in vitro spermatogenesis stimulating factors.

07:00 EST 1st January 2000 | BioPortfolio

Summary of "Discovering in vitro spermatogenesis stimulating factors."

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This article was published in the following journal.

Name: Cell death & disease
ISSN: 2041-4889
Pages: e1937

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Medical and Biotech [MESH] Definitions

Glycoproteins found in a subfraction of normal mammalian plasma and urine. They stimulate the proliferation of bone marrow cells in agar cultures and the formation of colonies of granulocytes and/or macrophages. The factors include INTERLEUKIN-3; (IL-3); GRANULOCYTE COLONY-STIMULATING FACTOR; (G-CSF); MACROPHAGE COLONY-STIMULATING FACTOR; (M-CSF); and GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; (GM-CSF).

COLONY-STIMULATING FACTORS prepared by recombinant DNA technology.

Granulocyte-macrophage colony-stimulating factors prepared by recombinant DNA technology.

Cell surface receptors for colony stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of hemopoietic cells.

These growth factors comprise a family of hematopoietic regulators with biological specificities defined by their ability to support proliferation and differentiation of blood cells of different lineages. ERYTHROPOIETIN and the COLONY-STIMULATING FACTORS belong to this family. Some of these factors have been studied and used in the treatment of chemotherapy-induced neutropenia, myelodysplastic syndromes, and bone marrow failure syndromes.

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