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Can a single dose response predict the effect of montelukast on exercise-induced bronchoconstriction?

08:00 EDT 22nd October 2015 | BioPortfolio

Summary of "Can a single dose response predict the effect of montelukast on exercise-induced bronchoconstriction?"

Exercise-induced bronchoconstriction (EIB) can be prevented by a single dose of montelukast (MLK). The effect is variable, similar to the variable responsiveness observed after daily treatment with MLK. We hypothesized that the effect of a single MLK-dose (5 or 10 mg) on EIB could predict the clinical effectiveness of longer term once daily treatment.

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Name: Pediatric pulmonology
ISSN: 1099-0496
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