Track topics on Twitter Track topics that are important to you
A poly(ethylene glycol)-b-poly(L-lysine)-b-poly(styrene) (PEG-PLL-PS) triblock copolymer, which contains cationic PLL block as the middle block, is synthesized via the combination of ring-opening polymerization (ROP) and atom transfer radical polymerization (ATRP). The PEG-PLL-PS (ELS) triblock is employed as macromolecular surfactants to form stable oil-in-water (O/W) emulsion, which is subsequently applied as the template to prepare Janus silica hollow spheres (JHS) via one-pot biosilicification reaction. For the emulsion template, the middle PLL block assembles at the O/W interface and directs the biomi-metic silica synthesis in the presence of phosphate buffer and silicic acid precursors. This biosilicification process takes place only in the intermediate layer between water and organic interior phase, leading to the formation of silica JHSs with hydrophobic PS chains tethered on the inner surface and PEG attached on the outer surface. The three-layer JHSs, namely PEG/silica-polylysine/PS composites, were verified by electron microscopy. Further breaking these JHSs into species, polymer grafted Janus silica nanoplates (JPLs) can be obtained. Our studies provide an efficient one-step method to prepare hybrid silica Janus structures within minutes.
This article was published in the following journal.
Name: Langmuir : the ACS journal of surfaces and colloids
Hollow nanostructures are attractive for energy storage and conversion, drug delivery, and catalysis applications. Although these hollow nanostructures of compounds can be generated through the proces...
The composite carbon materials with multiple morphologies (such as spheres/sheets and spheres/tubes, and so on) that combine the merits of both structures have a wide range of applications in electroc...
In this work, instead of coupling with carbon-based materials, the obtained MoS hollow spheres constructed of many curved nanosheets have been successfully fabricated via one-pot hydrothermal process....
Numerous studies have focused on DNA as a generic material because of its unique ability to recognize specific sequences, range of biological functions, and simple molecular structure. However, the co...
Preparation of polymer-silica colloidal nanocomposite particles with concave shape is challenging and seldom reported. This paper presents a novel and facile method to prepare dimpled polymer-silica n...
The purpose of this study is to determine whether spherical silica can achieve similar or greater extrinsic dental stain and plaque removal, in comparison to dentifrices containing higher ...
The aim of the present study was to determine whether oral dosing, up to 9 grams/day, of porous silica administered as a food additive can be used safely in normal weight and obese male hu...
Janus stent is the only marketed drug-eluting stent (DES) without polymer coating as yet in China. The goal of this study is to evaluate the efficacy of JANUS (Tacrolimus eluted stent) i...
Selective Internal Radiation Therapy (SIRT), also known as radioembolisation, is a minimal invasive, endovascular treatment for primary and secondary liver tumours. In France, SIR-Spheres ...
The main purpose of this study is to determine the safety and toxicity of treatment with SIR-Spheres® in patients with unresectable primary liver cancer or hepatocellular carcinoma (HCC)....
Agents that inhibit JANUS KINASES.
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.
A non-crystalline form of silicon oxide that has absorptive properties. It is commonly used as a desiccating agent and as a stationary phase for CHROMATOGRAPHY. The fully hydrated form of silica gel has distinct properties and is referred to as SILICIC ACID.
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS.
An interleukin-21 receptor subunit that combines with the INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT to form a high affinity receptor for interleukin-21. It signals via interaction of its cytoplasmic domain with JANUS KINASES such as JANUS KINASE 1 and JANUS KINASE 3.