Transcriptomics: a sword to cut the Gordian knot of traditional Chinese medicine.

08:00 EDT 26th October 2015 | BioPortfolio

Summary of "Transcriptomics: a sword to cut the Gordian knot of traditional Chinese medicine."

The systemic effects of traditional Chinese medicine (TCM) seem to be a Gordian knot, impossible to untie for decades. With the advent of transcriptomics, a useful sword is provided to cut the knot and shed some light on complex bioprocesses and intrinsic connections among them. Here, we revisit studies on TCM ZHENGs using this approach, highlight its applications on elucidating the potential scientific basis of ZHENG and investigating mechanisms of action for the TCM formula, and demonstrating its unique role in novel TCM drug design and discovery through active ingredient detection from TCM and compatibility theory study of TCM. The limitations and future perspectives of transcriptomics approaches to TCM study are also discussed.


Journal Details

This article was published in the following journal.

Name: Biomarkers in medicine
ISSN: 1752-0371


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A system of traditional medicine which is based on the beliefs and practices of the Chinese culture.

A genus in the family Monascaceae, order EUROTIALES. One species, Monascus purpureus, has multiple uses in traditional Chinese medicine (MEDICINE, CHINESE TRADITIONAL).

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