Advertisement

Topics

Recent 5-year Findings and Technological Advances in the Proteomic Study of HIV-associated Disorders.

08:00 EDT 5th April 2017 | BioPortfolio

Summary of "Recent 5-year Findings and Technological Advances in the Proteomic Study of HIV-associated Disorders."

Human immunodeficiency virus-1 (HIV-1) mainly relies on host factors to complete its life cycle. Hence, it is very important to identify HIV-regulated host proteins. Proteomics is an excellent technique for this purpose because of its high throughput and sensitivity. In this review, we summarized current technological advances in proteomics, including general isobaric tags for relative and absolute quantitation (iTRAQ) and stable isotope labeling by amino acids in cell culture (SILAC), as well as subcellular proteomics and investigation of posttranslational modifications. Furthermore, we reviewed the applications of proteomics in the discovery of HIV-related diseases and HIV infection mechanisms. Proteins identified by proteomic studies might offer new avenues for the diagnosis and treatment of HIV infection and the related diseases.

Affiliation

Journal Details

This article was published in the following journal.

Name: Genomics, proteomics & bioinformatics
ISSN: 2210-3244
Pages:

Links

DeepDyve research library

PubMed Articles [32637 Associated PubMed Articles listed on BioPortfolio]

Recent advances in proteomic profiling of pancreatic ductal adenocarcinoma and the road ahead.

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide. However, there remain many unmet clinical needs, from diagnosis to treatment strategies. The inherent complexity of t...

Highly multiplexed single-cell protein analysis.

Single-cell proteomic analysis is crucial to advance our understanding of normal physiology and disease pathogenesis. The comprehensive protein profiling in individual cells of a heterogeneous sample ...

Toward a Wiring Diagram Understanding of Appetite Control.

Prior mouse genetic research has set the stage for a deep understanding of appetite regulation. This goal is now being realized through the use of recent technological advances, such as the ability to...

Rethinking m(6)A Readers, Writers, and Erasers.

In recent years, m(6)A has emerged as an abundant and dynamically regulated modification throughout the transcriptome. Recent technological advances have enabled the transcriptome-wide identification ...

Recent advances in reconstructing microbial secondary metabolites biosynthesis in Aspergillus spp.

High throughput genome sequencing has revealed a multitude of potential secondary metabolites biosynthetic pathways that remain cryptic. Pathway reconstruction coupled with genetic engineering via het...

Clinical Trials [4868 Associated Clinical Trials listed on BioPortfolio]

Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family History of Cross-Eye

Little is known about the development of the ocular, or eye, motor system (the parts of the brain that control how the eyes move) in children. Recent technological and methodological adva...

Prognostic Value of SPECT-CT Quantitative Indices for the Response Assessment of Bone Metastatic Prostate Carcinoma

Prognostic interest of bone scintigraphy in bone metastatic prostate carcinoma (BMPC) has been shown. Recent technological advances allow to perform quantitative bone SPECT-CT in routine p...

The GLOBAL Vitamin D Study. A Genomic, Transcriptomic, Proteomic and Metabolomic Approach

The effect of vitamin D supplementation on genetic, proteomic , and metabolomic profile in adipose tissue will be studied in 50 subjects.

Bipolar Proteomic Assay Validation Study

The purpose of this study is to validate a set of signatures, based on a panel of proteomic markers, that discriminate BDI, BDII, and MDD in people seeking treatment for a depressive episo...

Breast Cancer Proteomics and Molecular Heterogeneity

Primary objective: The primary objective is to define the proteomic and molecular characteristics of primary and recurrent/ metastatic breast tumours with special focus on the expression ...

Medical and Biotech [MESH] Definitions

Educational programs designed to inform dentists of recent advances in their fields.

Educational programs designed to inform physicians of recent advances in their field.

Educational programs designed to inform nurses of recent advances in their fields.

Educational programs designed to inform graduate pharmacists of recent advances in their particular field.

Educational programs designed to inform individuals of recent advances in their particular field of interest. They do not lead to any formal advanced standing.

Advertisement
Quick Search
Advertisement
Advertisement

 


DeepDyve research library

Relevant Topics

AIDS and HIV
AIDS; Acquired Immune Deficiency Syndrome. HIV; Human Immunodeficiency Virus HIV infection causes AIDS. HIV infection also causes the production of anti-HIV antibodies, which forms the test for HIV in patients. People who have the HIV antibodies are ...

Human Immuno Deficiency Virus (HIV)
Human Immunodeficiency Virus (HIV), the causative agent of AIDS. The Human Immunodeficiency Virus, more commonly known as HIV, is a member of the lentivirus sub-set of the retrovirus family of pathogens. It causes AIDS, or Acquired Immuno Deficiency Sy...


Searches Linking to this Article