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A recent study suggests that the prefrontal cortex gradually becomes critical as a storage site for remotely acquired memories. How do we interpret this observation in light of the well-known functional role of the prefrontal cortex in cognition and memory?
This article was published in the following journal.
Name: Current biology : CB
Systems-level consolidation refers to the time-dependent reorganisation of memory traces in the neocortex, a process in which the ventromedial prefrontal cortex (vmPFC) has been implicated. Capturing ...
Repeated encounter with encoded memories is often a fundamental component of long-term learning processes, however, the role of repeated access to encoded memories in long-term consolidation is yet to...
NMDA receptor (NMDAr) hypofunction has been widely used as a schizophrenia model. Decreased activation of NMDAr is associated with a disrupted excitation/inhibition balance in the prefrontal cortex an...
Memory enhancement and memory decline are two opposing cognitive performances commonly observed in clinical practice, yet the neural mechanisms underlying these two different phenomena remain poorly u...
The anterior thalamic nuclei (ATN) are a major interface between the hippocampus and prefrontal cortex within an extended Papez circuit. Rat models suggest that the deficits caused by ATN damage, whic...
The main objective of this study is to examine the effects of magnetic stimulation on the prefrontal cortex. We plan to use low frequency, repeated transcranial magnetic stimulation (1 Hz...
This study evaluates the efficacy of 5Hz repetitive Transcranial Magnetic Stimulation (rTMS) over Left Dorsolateral Prefrontal Cortex and Dorsomedial Prefrontal Cortex on Major Depressive ...
The purpose of this study is to compare two slightly different methods of transcranial magnetic stimulation (TMS) to treat Post Traumatic Stress Disorder (PTSD)
This study investigates the relationship between prefrontal cortex activity and antisocial and aggressive behavior, and risk factors for such behavior. In the double-blind, randomized cont...
The purpose of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (DLPFC) on language production.
The rostral part of the frontal lobe, bounded by the inferior precentral fissure in humans, which receives projection fibers from the mediodorsal nucleus of the thalamus. The prefrontal cortex receives afferent fibers from numerous structures of the diencephalon, mesencephalon, and limbic system as well as cortical afferents of visual, auditory, and somatic origin.
A composite area of the cerebral cortex concerned with motor control and sensory perception comprising the motor cortex areas, the somatosensory areas, the gustatory cortex, the olfactory areas, the auditory cortex, and the visual cortex.
The cytoarchitecturally well-defined area of multilaminate cerebral cortex on the medial aspect of the parahippocampal gyrus, immediately caudal to the olfactory cortex of the uncus. The entorhinal cortex is the origin of the major neural fiber system afferent to the hippocampus, the so-called PERFORANT PATHWAY. (Stedman, 25th ed)
An area in the temporal lobe that is important for memory encoding and retrieval. It is bordered caudally by the parahippocampal cortex (see HIPPOCAMPUS) and ventrally and medially by the ENTORHINAL CORTEX.
Treatment of chronic, severe and intractable psychiatric disorders by surgical removal or interruption of certain areas or pathways in the brain, especially in the prefrontal lobes.