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Are more trials of calcium supplements really needed? A response to Bolland et al.

08:00 EDT 7th July 2017 | BioPortfolio

Summary of "Are more trials of calcium supplements really needed? A response to Bolland et al."

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This article was published in the following journal.

Name: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
ISSN: 1433-2965
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Medical and Biotech [MESH] Definitions

Calcium compounds used as food supplements or in food to supply the body with calcium. Dietary calcium is needed during growth for bone development and for maintenance of skeletal integrity later in life to prevent osteoporosis.

Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.

Membrane-associated calcium-binding proteins that are characterized by N-terminal EF HAND MOTIFS and a STERILE ALPHA MOTIF. They function as sensors of ENDOPLASMIC RETICULUM calcium levels and translocate from the ER to the plasma membrane to activate CALCIUM CHANNELS in response to intracellular calcium depletion.

A stromal interaction molecule that functions as a highly sensitive calcium sensor in the ENDOPLAMSIC RETICULUM and CYTOSOL. It can regulate CALCIUM RELEASE ACTIVATED CALCIUM CHANNELS in response to minor variations in intracellular calcium.

A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.

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