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Effect of Whole Body Hypothermia on Surfactant Function When Amniotic Fluid is Meconium Stained.

08:00 EDT 14th July 2017 | BioPortfolio

Summary of "Effect of Whole Body Hypothermia on Surfactant Function When Amniotic Fluid is Meconium Stained."

We provide the first complete biophysical study of surfactant by captive bubble surfactometry from a neonate with meconium-stained amniotic fluid under controlled whole body hypothermia. Surfactant function improves after 48 hours of hypothermia, as surfactant cholesterol decreases. These findings partially explain positive effect of hypothermia on respiratory outcomes during meconium aspiration syndrome. A larger study including several neonates with or without lung disease is being conducted to better define the effect of hypothermia on surfactant function.

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This article was published in the following journal.

Name: Therapeutic hypothermia and temperature management
ISSN: 2153-7933
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Medical and Biotech [MESH] Definitions

Abnormally low BODY TEMPERATURE that is intentionally induced in warm-blooded animals by artificial means. In humans, mild or moderate hypothermia has been used to reduce tissue damages, particularly after cardiac or spinal cord injuries and during subsequent surgeries.

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