MicroRNA mediated regulation of immunity against gram-negative bacteria.

08:00 EDT 11th August 2017 | BioPortfolio

Summary of "MicroRNA mediated regulation of immunity against gram-negative bacteria."

Evidence over the last couple decades has comprehensively established that short, highly conserved, non-coding RNA species called microRNA (miRNA) exhibit the ability to regulate expression and function of host genes at the messenger RNA (mRNA) level. MicroRNAs play key regulatory roles in immune cell development, differentiation, and protective function. Intrinsic host immune response to invading pathogens rely on intricate orchestrated events in the development of innate and adaptive arms of immunity. We discuss the involvement of miRNAs in regulating these processes against gram negative pathogens in this review.


Journal Details

This article was published in the following journal.

Name: International reviews of immunology
ISSN: 1563-5244
Pages: 1-13


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Medical and Biotech [MESH] Definitions

A large group of aerobic bacteria which show up as pink (negative) when treated by the gram-staining method. This is because the cell walls of gram-negative bacteria are low in peptidoglycan and thus have low affinity for violet stain and high affinity for the pink dye safranine.

A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.

A large group of anaerobic bacteria which show up as pink (negative) when treated by the Gram-staining method.

Bacteria which lose crystal violet stain but are stained pink when treated by Gram's method.

Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method.

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