Informed Consent and Decision Making Among Participants in Novel-Design Phase I Oncology Trials.

08:00 EDT 24th August 2017 | BioPortfolio

Summary of "Informed Consent and Decision Making Among Participants in Novel-Design Phase I Oncology Trials."

Although phase I clinical trials are the gateway to progress in cancer therapies, this setting poses ethical challenges to ensure that patients provide consent free from misunderstandings of therapeutic intent or unrealistic expectations of benefit. The design of phase I oncology trials has evolved rapidly over time and today includes more targeted agents and combinations of experimental drugs with standard drugs, which may further complicate how patients understand phase I research participation.


Journal Details

This article was published in the following journal.

Name: Journal of oncology practice
ISSN: 1935-469X
Pages: JOP2017021303


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Medical and Biotech [MESH] Definitions

Groups of persons whose range of options is severely limited, who are frequently subjected to COERCION in their DECISION MAKING, or who may be compromised in their ability to give INFORMED CONSENT.

Mathematical or statistical procedures used as aids in making a decision. They are frequently used in medical decision-making.

Informed consent given by someone other than the patient or research subject.

Informed consent given by a parent on behalf of a minor or otherwise incompetent child.

Use of an interactive computer system designed to assist the physician or other health professional in choosing between certain relationships or variables for the purpose of making a diagnostic or therapeutic decision.

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