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In vitro efficacy of disinfectants utilised for skin decolonization and environmental decontamination during a hospital outbreak with Candida auris.

08:00 EDT 5th September 2017 | BioPortfolio

Summary of "In vitro efficacy of disinfectants utilised for skin decolonization and environmental decontamination during a hospital outbreak with Candida auris."

Candida auris has caused nosocomial infections and transmissions within hospital settings. As little is known about the efficacy of skin and environmental decontamination products to kill C. auris this study investigated the in vitro activity of chlorine, chlorhexidine, iodine povidone and vaporized hydrogen peroxide products against C. auris. H2 O2 vapour showed 96.6-100% effective killing of C. auris. All isolates were inhibited by chlorhexidine gluconate concentrations at 0.125 to 1.5% and for iodinated povidone at 0.07-1.25%. Other species of Candida were also killed at 1000ppm chlorine except C. parapsilosis which failed to be killed at 3 minutes contact time. We conclude that chlorhexidine gluconate, iodinated povidone, chlorine and H2 O2 vapour demonstrate effective killing activity against C. auris at concentrations used in clinical practice. This article is protected by copyright. All rights reserved.

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Name: Mycoses
ISSN: 1439-0507
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