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IGF2 stimulates fetal growth in a sex and organ dependent manner.

08:00 EDT 14th September 2017 | BioPortfolio

Summary of "IGF2 stimulates fetal growth in a sex and organ dependent manner."

IGF2 is a key determinant of fetal growth, and altered expression of IGF2 is implicated in fetal growth disorders and maternal metabolic derangements including gestational diabetes. Here we studied how increased levels of IGF2 in late pregnancy affect fetal growth.

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This article was published in the following journal.

Name: Pediatric research
ISSN: 1530-0447
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Medical and Biotech [MESH] Definitions

The potential of the FETUS to survive outside the UTERUS after birth, natural or induced. Fetal viability depends largely on the FETAL ORGAN MATURITY, and environmental conditions.

The failure of a FETUS to attain its expected FETAL GROWTH at any GESTATIONAL AGE.

A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.

A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.

Functional competence of specific organs or body systems of the FETUS in utero.

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