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Sulfamethoxazole/trimethoprim vs Fluoroquinolones for the Treatment of Stenotrophomonas maltophilia Bloodstream Infections.

08:00 EDT 27th September 2017 | BioPortfolio

Summary of "Sulfamethoxazole/trimethoprim vs Fluoroquinolones for the Treatment of Stenotrophomonas maltophilia Bloodstream Infections."

Stenotrophomonas maltophilia causes high mortality rates, especially in bloodstream infections (BSI) where there is a lack of comparative data with fluoroquinolones (FQs) and sulfamethoxazole/trimethoprim (TMP/SMX). The objective of this study was to evaluate outcomes in patients with S. maltophilia BSIs that are treated with FQs vs. TMP/SMX.

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This article was published in the following journal.

Name: Journal of global antimicrobial resistance
ISSN: 2213-7173
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Medical and Biotech [MESH] Definitions

A species of STENOTROPHOMONAS, formerly called Xanthomonas maltophilia, which reduces nitrate. It is a cause of hospital-acquired ocular and lung infections, especially in those patients with cystic fibrosis and those who are immunosuppressed.

A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.

A drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

This drug combination has proved to be an effective therapeutic agent with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. It is effective in the treatment of many infections, including PNEUMOCYSTIS PNEUMONIA in AIDS.

Nonsusceptibility of bacteria to the action of TRIMETHOPRIM.

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