Toxicity and Sublethal Effects of Cantharidin on Musca domestica (Diptera: Muscidae).

08:00 EDT 27th September 2017 | BioPortfolio

Summary of "Toxicity and Sublethal Effects of Cantharidin on Musca domestica (Diptera: Muscidae)."

The house fly, Musca domestica L. (Diptera: Muscidae), is a major pest of medical and veterinary importance all over the world. Management efforts for house flies are usually compromised owing to their resistance to many groups of conventional insecticides. Cantharidin, a natural toxin produced by meloid beetles, is a biopesticide with a reported toxicity to some insect pests including house flies. However, the effects of cantharidin on biological and fitness parameters of house flies have not yet been investigated. In the present study, we investigated the toxicity and sublethal effects of cantharidin on biological parameters of house flies for two consecutive generations. The results revealed that the values of LC50, LC25, LC10, and LC2 against house flies were to be 2.45, 1.23, 0.66, and 0.30 mg/liter, respectively. Sublethal effects of these concentrations on the development and reproduction parameters of house flies revealed that cantharidin reduced population growth by affecting pupation rate, adult emergence, and by lengthening developmental time. The female ratio, fecundity, egg hatching, and survival of adult flies were significantly reduced at LC2, LC10, LC25, and LC50 of cantharidin when compared with the control group. Furthermore, the increase in concentration of cantharidin had a significant effect on reducing the mean values of mean relative growth rate, net reproductive rate (Ro), intrinsic rate of natural increase (rm), and biotic potential (bp). In conclusion, the results of this study revealed the toxicity of cantharidin against house flies and the adverse effects of sublethal concentrations on biological parameters which may have positive implications for effective management of house flies.


Journal Details

This article was published in the following journal.

Name: Journal of economic entomology
ISSN: 1938-291X


DeepDyve research library

PubMed Articles [14646 Associated PubMed Articles listed on BioPortfolio]

Determination of the Genetic and Synergistic Suppression of a Methoxyfenozide-Resistant Strain of the House Fly Musca domestica L. (Diptera: Muscidae).

Musca domestica Linnaeus (house fly, Diptera: Muscidae) is a major veterinary and medical important pest all over the world. These flies have ability to develop resistance to insecticides. The present...

Development of Musca domestica at constant temperatures and the first case report of its application for estimating the minimum postmortem interval.

Musca domestica Linnaeus, 1758 (Diptera: Muscidae) is an important cosmopolitan pest with potential forensic value. Thus, the investigation of the development of M. domestica is of vital significance ...

Mortality of the House Fly (Diptera: Muscidae) After Exposure to Combinations of Beauveria bassiana (Hypocreales: Clavicipitaceae) With the Polyol Sweeteners Erythritol and Xylitol.

Documented resistance to traditional insecticides in the house fly, Musca domestica L. (Diptera: Muscidae), has expedited a need for alternative forms of control. One such method is the use of biologi...

Biological Evaluation of Endothall, a Dicarboxylic Acid Analog of Norcantharidin, and Cantharidin on Oriental Leafworm, Spodoptera litura (Lepidoptera: Noctuidae).

Cantharidin is a highly potent toxin produced by insects belonging to the order Coleoptera and family Meloidae. The insecticidal activity of cantharidin against different orders of insects has been we...

Monitoring of toxicity of As(V) solutions by AMPHITOX test without and with treatment with zerovalent iron nanoparticles.

Changes in toxicity of As(V) solutions from acute to chronic exposure have been evaluated by the AMPHITOX test. This test employs Rhinella arenarum, a widely distributed toad in Argentine areas. LOEC ...

Clinical Trials [2971 Associated Clinical Trials listed on BioPortfolio]

Efficacy of Cantharidin in Molluscum Contagiosum

The University of North Carolina Department of Dermatology is conducting a clinical trial to evaluate a drug called cantharidin in the treatment of molluscum contagiosum. Molluscum is a c...

Cantharidin-induced Skin Blister for Testing Anti-inflammatory Effects of Macrolides

The purpose of this study is to investigate the utility of the cantharidin-induced skin blister assay for evaluation of the anti-inflammatory effects of macrolides in healthy male voluntee...

Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum

The purpose of this study is to determine if cantharidin is a safe and effective treatment for molluscum contagiosum in kids

Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum, Phase 2

Cantharidin is cited in the dermatology and pediatric literature as a valuable treatment option. Treatment is often available in private practice offices, where a prescribing physician may...

The Efficacy and Safety of Curcuma Domestica Extracts and Ibuprofen in Knee Osteoarthritis

Osteoarthritis of knee is common degenerative musculoskeletal diseases. Non-steroidal antiinflammatory drugs (NSAIDs) are used to decrease pain symptom but someone can not tolerate its gas...

Medical and Biotech [MESH] Definitions

A family of the order DIPTERA with over 700 species. Important species that may be mechanical vectors of disease include Musca domesticus (HOUSEFLIES), Musca autumnalis (face fly), Stomoxys calcitrans (stable fly), Haematobia irritans (horn fly) and Fannia spp.

Flies of the species Musca domestica (family MUSCIDAE), which infest human habitations throughout the world and often act as carriers of pathogenic organisms.

An order of the class Insecta. Wings, when present, number two and distinguish Diptera from other so-called flies, while the halteres, or reduced hindwings, separate Diptera from other insects with one pair of wings. The order includes the families Calliphoridae, Oestridae, Phoridae, Sarcophagidae, Scatophagidae, Sciaridae, SIMULIIDAE, Tabanidae, Therevidae, Trypetidae, CERATOPOGONIDAE; CHIRONOMIDAE; CULICIDAE; DROSOPHILIDAE; GLOSSINIDAE; MUSCIDAE; TEPHRITIDAE; and PSYCHODIDAE. The larval form of Diptera species are called maggots (see LARVA).

Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.

A schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.

Quick Search


DeepDyve research library

Relevant Topic

Biological Therapy
Biological therapy involves the use of living organisms, substances derived from living organisms, or laboratory-produced versions of such substances to treat disease. Some biological therapies for cancer use vaccines or bacteria to stimulate the body&rs...

Searches Linking to this Article