EEG Dynamics of a Go/Nogo Task in Children with ADHD.
Summary of "EEG Dynamics of a Go/Nogo Task in Children with ADHD."
Studies investigating event-related potential (ERP) evoked in a Cue-Go/NoGo paradigm have shown lower frontal N1, N2 and central P3 in children with attention-deficit/hyperactivity disorder (ADHD) compared to typically developing children (TDC). However, the electroencephalographic (EEG) dynamics underlying these ERPs remain largely unexplored in ADHD.
Affiliation
Journal Details
This article was published in the following journal.
Name: Brain sciences
ISSN: 2076-3425
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/29261133
- DOI: http://dx.doi.org/10.3390/brainsci7120167
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Medical and Biotech [MESH] Definitions
Nogo Proteins
Myelin proteins that are expressed as three isoforms: Nogo-A, Nogo-B, and Nogo-C. These share a C-terminal reticulon homology domain (RHD), consisting of two hydrophobic membrane domains flanking a 66 amino acid (Nogo-66) hydrophilic region. A long transmembrane region allows conformations that either span the entire membrane or fold into a hairpin conformation. Nogo inhibits NEURITE outgrowth and modulates wiring and the restriction of SYNAPTIC PLASTICITY in the adult central nervous system. It also regulates neurite fasciculation, branching, and extension in the developing nervous system.
Nogo Receptors
GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini that are connected to the GPI by a "stalk" region rich in prolines, serines and threonines. They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED GLYCOPROTEIN and other cell surface glycoproteins. Interactions between nogo receptors and their ligands modulate nerve growth and NEURONAL PLASTICITY.
Nogo Receptor 2
A Nogo receptor that binds to MYELIN-ASSOCIATED GLYCOPROTEIN. It localizes to the GROWTH CONES of neurons in the THALAMUS; CORTEX: AMYGDALA; OLFACTORY BULBS; and HYPOTHALAMUS.
Time And Motion Studies
The observation and analysis of movements in a task with an emphasis on the amount of time required to perform the task.
Nogo Receptor 1
A high affinity receptor for myelin-associated inhibitors (MAIs) that include NOGO-A PROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; and MYELIN-ASSOCIATED GLYCOPROTEIN. It is expressed primarily by neurons in the brain and OLFACTORY BULBS. During embryonic development, it is expressed in the PERIPHERAL NERVOUS SYSTEM. It localizes to GROWTH CONES and may inhibit neurite outgrowth following SPINAL INJURY.
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