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The therapeutic role of Rifampicin in Alzheimer's Disease.

07:00 EST 8th January 2018 | BioPortfolio

Summary of "The therapeutic role of Rifampicin in Alzheimer's Disease."

Rifampicin exerts significant brain protective functions in multiple experimental models. Here we summarized the underlying mechanisms of the neuroprotective and pro-cognitive effects of rifampicin that is mediated by its anti-inflammatory, anti-tau, anti-amyloid and cholinergic effects. Beyond suggesting that rifampicin shows strong brain protective effects in preclinical models of Alzheimer's Disease we also have provided substantial clinical evidence for the neuroprotective and pro-cognitive effects of rifampicin. Future neuroimaging studies in combined with the clinical assessment scores would be the following steps to be taken in this field of research.

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This article was published in the following journal.

Name: Psychiatry and clinical neurosciences
ISSN: 1440-1819
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