Are meta-analyses clinically useful?

07:00 EST 1st February 2018 | BioPortfolio

Summary of "Are meta-analyses clinically useful?"

No Summary Available


Journal Details

This article was published in the following journal.

Name: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
ISSN: 1547-3325
Pages: 1-2


DeepDyve research library

PubMed Articles [9049 Associated PubMed Articles listed on BioPortfolio]

Older studies can underestimate prognosis of glioblastoma biomarker in meta-analyses: a meta-epidemiological study for study-level effect in the current literature.

There are many potential biomarkers in glioblastoma (GBM), and meta-analyses represent the highest level of evidence when inferring their prognostic significance. It is possible however, that inherent...

Meta-analysis of meta-analyses in oncologic positron emission tomography.

As PET has become a standard of treatment in patients with cancer, publications of oncologic PET have grown sharply. We aimed to organize the data of meta-analyses of oncologic PET and assess the qual...

The Use of Statins for Antipsychotic Augmentation in Schizophrenia: Examination of Meta-Analyses With Flawed Methods and Conclusions.

A very large number of psychopharmacologic agents have been trialed as antipsychotic augmentation strategies for the improvement of positive, negative, mood, cognitive, and other symptoms of schizophr...

Evaluating Mediterranean diet and risk of chronic disease in cohort studies: an umbrella review of meta-analyses.

Several meta-analyses have been published summarizing the associations of the Mediterranean diet (MedDiet) with chronic diseases. We evaluated the quality and credibility of evidence from these meta-a...

The Evaluation of Bivariate Mixed Models in Meta-analyses of Diagnostic Accuracy Studies with SAS, Stata and R.

Meta-analyses require a thoroughly planned procedure to obtain unbiased overall estimates. From a statistical point of view not only model selection but also model implementation in the software affec...

Clinical Trials [1130 Associated Clinical Trials listed on BioPortfolio]

Meta-Analysis of Drug Therapy in Patients With Severe Alcoholic Hepatitis

In the specific setting of the evaluation of corticosteroids, pentoxifylline of their combination in severe alcoholic hepatitis, only meta-analysis combining individual data is able to pro...

Vitamin D Supplements on Markers for Cardiovascular Disease and Diabetes: an Individual Participant Data Meta-analysis

This meta-analysis will be conducted to study the effect on vitamin D supplements on markers for cardiovascular disease and diabetes using individual participant data from 12 RCTs. Given t...

Review and Assessment of Network Meta-analyses for Knowledge Uptake Study

This randomized controlled trial will assess the interpretability of the rank-heat plot for presenting the results of network meta-analysis in comparison to SUCRA (surface under the cumula...

Variability of Definitions for Survival Endpoints and Surrogate Properties for OS: a Meta-analysis

The DATECAN-2 project aims at assessing the surrogate properties for OS of several time-to-event endpoints through meta-analyses of completed and published randomized controlled trials. Tw...

Data Analyses for Ancillary WISE Femhrt Hormone Replacement Study

For the purposes of this study, as a core lab coordinating center, the investigators will be performing P31 MRS core lab analyses; hormone core lab analyses; lipid core lab analyses; gluco...

Medical and Biotech [MESH] Definitions

Meta-analysis of randomized trials in which estimates of comparative treatment effects are visualized and interpreted from a network of interventions that may or may not have been evaluated directly against each other. Common considerations in network meta-analysis include conceptual and statistical heterogeneity and incoherence.

The influence of study results on the chances of publication and the tendency of investigators, reviewers, and editors to submit or accept manuscripts for publication based on the direction or strength of the study findings. Publication bias has an impact on the interpretation of clinical trials and meta-analyses. Bias can be minimized by insistence by editors on high-quality research, thorough literature reviews, acknowledgement of conflicts of interest, modification of peer review practices, etc.

Works consisting of studies using a quantitative method of combining the results of independent studies (usually drawn from the published literature) and synthesizing summaries and conclusions which may be used to evaluate therapeutic effectiveness, plan new studies, etc. It is often an overview of clinical trials. It is usually called a meta-analysis by the author or sponsoring body and should be differentiated from reviews of literature.

Benzene derivatives which are substituted with two nitro groups in the ortho, meta or para positions.

Critical analyses of books or other monographic works.

Quick Search

DeepDyve research library

Searches Linking to this Article