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Engineering E. coli for simultaneous glucose-xylose utilization during methyl ketone production.

07:00 EST 27th January 2018 | BioPortfolio

Summary of "Engineering E. coli for simultaneous glucose-xylose utilization during methyl ketone production."

We previously developed an E. coli strain that overproduces medium-chain methyl ketones for potential use as diesel fuel blending agents or as flavors and fragrances. To date, the strain's performance has been optimized during growth with glucose. However, lignocellulosic biomass hydrolysates also contain a substantial portion of hemicellulose-derived xylose, which is typically the second most abundant sugar after glucose. Commercialization of the methyl ketone-producing technology would benefit from the increased efficiency resulting from simultaneous, rather than the native sequential (diauxic), utilization of glucose and xylose.

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This article was published in the following journal.

Name: Microbial cell factories
ISSN: 1475-2859
Pages: 12

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