Track topics on Twitter Track topics that are important to you
Increasing attention has been given to working memory (WM) impairment in Parkinson's disease (PD) patients. Previous studies revealed that the space-orientated feature-based filtering (target and distractors in distinct locations) was impaired in PD patients. However, the object-orientated feature-based filtering (target and distractor information pertaining to one object) ability in PD patients remains unclear. In this study, we examined the object-orientated feature-based filtering ability of 14 PD patients and 14 healthy controls in a change detection task under EEG monitoring. Participants were asked to remember the colors of two different objects while ignoring their shapes. Critically, the irrelevant feature could be changed in the probe. A failure in complete feature-based filtering would lead to an "irrelevant-change distracting effect," where the change of the irrelevant feature would impair the performance of the target feature, and lead to an enhanced anterior N2. We found that the distracting effect was larger in PD patients than in the control group in terms of d'; however, the N2 amplitude evoked by the irrelevant change was smaller in PD patients than in the control group. These results suggested that the object-orientated feature-based filtering ability was impaired in PD, which might derive from the deficit of their executive control.
This article was published in the following journal.
An ongoing debate in visual working memory research is concentrated on whether visual working memory capacity is determined solely by the number of objects to be memorized, or additionally by the numb...
Working memory has been shown to be strongly related to fluid intelligence; however, our goal is to shed further light on the process of information compression in working memory as a determining fact...
In order to efficiently process incoming visual information, selective attention acts as a filter that enhances relevant and suppresses irrelevant information. In this study, we used an event-related ...
The goal of the present study was to test whether the amount of coaching influenced the results of working memory training on both visual and verbal working memory. Additionally, the effects of the wo...
Theories of the locus of visual selective attention dysfunction in schizophrenia propose that the deficits arise from either an inability to maintain working memory representations that guide attentio...
This study is an investigation of the effect of a computer-based working memory training program on memory and language processing in at-risk children (e.g., those with working memory weak...
Impairments of cognition are a core, severely disabling feature of schizophrenia leading to poor long-term outcome with no established treatment available. Particularly impaired executive...
Anxiety levels among the younger generation especially students have been increasing drastically in recent years. This severely affects a student's academics as previous studies have shown...
According to the working memory model, which accounts for the organisation of working memory, the processing of non-meaningful gestures is not clear. Some authors suggest that working memo...
The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.
Temporary visual deficit or impaired visual processing occurring in a rapid serial visual presentation task. After a person identifies the first of two visual targets, the ability to detect the second target is impaired for the next few hundred milliseconds. This phenomenon is called attentional blink.
Neurological process involving the conversion of learned information into long-term memory.
A set of cognitive functions that controls complex, goal-directed thought and behavior. Executive function involves multiple domains, such as CONCEPT FORMATION, goal management, cognitive flexibility, INHIBITION control, and WORKING MEMORY. Impaired executive function is seen in a range of disorders, e.g., SCHIZOPHRENIA; and ADHD.
A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.
Temporary storage of information for a few seconds to hours, as opposed to long-term memory which refers to material stored for days, years, or a lifetime.
Parkinson's is a progressive neurological condition, affecting one person in every 500, 95% of which are over 40. It is caused by degeneration of more than 70% of the substantia nigra, which depletes the dopamine (the neurotransmitter involved in pro...